Results 11 to 20 of about 3,074,415 (252)

Discovery and Functional Analysis of Secondary Hair Follicle miRNAs during Annual Cashmere Growth. [PDF]

Int J Mol Sci, 2023
Secondary hair follicles (SHFs) produce the thermoregulatory cashmere of goats. MicroRNAs (miRNAs) play indispensable roles in hair follicle formation and growth. However, most studies examining miRNAs related to cashmere have been performed on goat skin. It remains unclear which miRNAs are highly expressed in SHFs or how miRNAs affect cashmere growth.
Wang M, Dai H, Sheng S, Liu Y, Zhang S, Bai W, Xue H.   +6 more
europepmc   +4 more sources

Melatonin promotes the development of the secondary hair follicles by regulating circMPP5

Journal of Animal Science and Biotechnology, 2023
Background The quality and yield of cashmere fibre are closely related to the differentiation and development of secondary hair follicles in the skin of cashmere goats.
Xiaogao Diao, Lingyun Yao, Tao Duan, Jiaxin Qin, Liwen He, Wei Zhang   +5 more
doaj   +3 more sources

Role of Csdc2 in Regulating Secondary Hair Follicle Growth in Cashmere Goats. [PDF]

Int J Mol Sci
Cashmere goats possess two types of hair follicles, with the secondary hair follicles producing valuable cashmere fiber used for textiles. The growth of cashmere exhibits a seasonal pattern arising from photoperiod change. Transcription factors play crucial roles during this process.
Zhu H, Li Y, Xu H, Ma Y, Andersson G, Bongcam-Rudloff E, Li T, Zhang J, Li Y, Han J, Yang M.   +10 more
europepmc   +5 more sources

Molecular Regulation of Secondary Hair Follicle Stem Cell by S100a4 in Cashmere Goat. [PDF]

Int J Mol Sci
Secondary hair follicle stem cells (HFSCs) are essential for cashmere fiber regeneration, yet the molecular mechanisms governing their activation and lineage progression remain poorly understood. Here, we identify S100a4 as a key regulator of secondary HFSCs in cashmere goat.
Liang X, Liu B, Wang J, Liu Y, Wei Y, Yu H, Zhang J, Zhang S, Xue H.   +8 more
europepmc   +4 more sources

Effect of inhibiting prolactin secretion on secondary hair follicle development in cashmere goats. [PDF]

Anim Biosci
Objective: This study aims to investigate the molecular mechanisms by which inhibiting prolactin (PRL) secretion affects secondary hair follicle (SHF) development in cashmere goats.Methods: A total of 20 cashmere goats were randomly assigned to either a bromocriptine (PRL inhibitor, BCT, 0.06 mg/kg BW) treatment (BCT+) or a control (BCT-) group.
Duan C, Yin X, Hao K, Zhang L, Xie Y, Li X, Liu Y, Zhang Y.   +7 more
europepmc   +3 more sources

Screening of microRNA and mRNA related to secondary hair follicle morphogenesis and development and functional analysis in cashmere goats. [PDF]

Funct Integr Genomics, 2022
Abstract microRNA (miRNA) is a type of endogenous short-chain non-coding RNA with regulatory function found in eukaryotes, which is involved in the regulation of a variety of cellular and biological processes. However, the research on the development of cashmere goat secondary hair follicles is still relatively scarce.
Shang F, Wang Y, Ma R, Rong Y, Wang M, Wu Z, Hai E, Pan J, Liang L, Wang Z, Wang R, Su R, Liu Z, Zhao Y, Wang Z, Li J, Zhang Y.   +16 more
europepmc   +3 more sources

Screening and expression validation of key proteins for secondary hair follicle growth in cashmere goats based on iTRAQ quantitative proteomics technology. [PDF]

Front Vet Sci
Chang J, Meng F, Zhang R, Feng J, Liu Y, Zhang J, Liu Z, Liang J, Xiao H.   +8 more
europepmc   +2 more sources

Epigenetic and transcriptional profiling of secondary hair follicle stem cells during cashmere growth. [PDF]

Sci Data
Cashmere grows from secondary hair follicles (SHFs), which serve as abundant reservoirs of synchronized stem cells responsible for the cyclical regeneration of cashmere. To investigate the epigenetic regulation of this process, we performed ChIP-seq targeting four key histone marks-H3K4me3, H3K27me3, H3K36me3 and H3K79me2 in isolated and cultured ...
Liang X, Liu B, Liu Y, Sheng S, Zhang X, Zhang J, Zhang S, Xue H.   +7 more
europepmc   +3 more sources

Thyroxine differentially modulates the peripheral clock: lessons from the human hair follicle [PDF]

, 2015
The human hair follicle (HF) exhibits peripheral clock activity, with knock-down of clock genes (BMAL1 and PER1) prolonging active hair growth (anagen) and increasing pigmentation.
Farjo, Nilofer, Haslam, Iain S., Hardman, Jonathan A., Paus, Ralf, Farjo, Bessam   +4 more
core   +5 more sources

Proteomics Reveals the Role of PLIN2 in Regulating the Secondary Hair Follicle Cycle in Cashmere Goats. [PDF]

Int J Mol Sci
Based on comprehensive proteomic analysis conducted across various stages of secondary hair follicles (SHFs), the growth and development regulatory mechanisms of SHFs in Jiangnan cashmere goats were studied. Proteomic analysis of skin tissue from the SHF anagen (An), catagen (Cn), and telogen (Tn) revealed 145 differentially expressed proteins (DEPs ...
Wu C, Lu Q, Ma S, Mamat N, Tang S, Liu W, Wang Y, Anwar A, Lu Y, Ma Q, Aimaier G, Fu X.   +11 more
europepmc   +3 more sources