Results 1 to 10 of about 22,247 (96)

(R,S)-2-{[4-(4-Methoxyphenyl)-5-phenyl-4H-1,2,4-triazol-3-yl] thio}-1-phenyl-1-ethanol

Molbank, 2021
4-(4-Methoxyphenyl)-5-phenyl--4H-1,2,4-triazole-3-thiol (4) was alkylated to 2-{[4-(-4-methoxyphenyl)-5-phenyl-4H-1,2,4-triazol-3-yl]thio}-1-phenylethan-1-one (5) in alkaline conditions using 2-bromo-1-phenylethanone.
Flavius-Gabriel Wurfer, Valentin Badea
doaj   +1 more source

(R,S)-2-{[4-(4-Methylphenyl)-5-phenyl-4H-1,2,4-triazol-3-yl]thio}-1-phenyl-1-ethanol

Molbank, 2021
4-(4-Methylphenyl)-5-phenyl-4H-1,2,4-triazol-3-thiol (4) was alkylated to 2-{[4-(4-methylphenyl)-5-phenyl-4H-1,2,4-triazol-3-yl]thio}-1-phenylethan-1-one (5) in alkaline conditions using 2-bromo-1-phenylethanone. The alkylated compound (5) was reduced at
Vladislav-Silvestru Valicsek, Valentin Badea   +1 more
doaj   +1 more source

(±)-2-{[4-(4-Bromophenyl)-5-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenyl-1-ethanol

Molbank, 2021
The novel racemic secondary alcohol (±)-2-{[4-(4-bromophenyl)-5-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-1-phenyl-1-ethanol (12) has been successfully synthesized through S-alkylation of 4-(4-bromophenyl)-5-phenyl-4H-1,2,4-triazole-3-thiol (10) in alkaline
Milenca Mariana Vorga, Valentin Badea
doaj   +1 more source

Synthesis and study of the anticancer activity of some new 7H-[1,2,4]triazolo [3,4-b][1,3,4]thiadiazines

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2021
The problem of finding effective low-toxic anticancer agents is one of the most important in modern medicine and pharmacy. Despite a large selection of anticancer drugs and a variety of mechanisms of their action, the effectiveness of existing drugs ...
I. I. Myrko, T. I. Chaban, V. V. Ohurtsov, I. V. Drapak, V. S. Matiichuk   +4 more
doaj   +1 more source

Transesterification/Acylation of Secondary Alcohols Mediated by N-Heterocyclic Carbene Catalysts [PDF]

The Journal of Organic Chemistry, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Rohit, Singh, Rebecca M, Kissling, Marie-Anne, Letellier, Steven P, Nolan   +3 more
openaire   +2 more sources

Enantioselective Acylation of Secondary Alcohols Catalyzed by Chiral N-Heterocyclic Carbenes [PDF]

Organic Letters, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Taichi, Kano, Kouji, Sasaki, Keiji, Maruoka   +2 more
openaire   +2 more sources

β‐Alkylation through Dehydrogenative Coupling of Primary Alcohols and Secondary Alcohols Catalyzed by Thioether‐Functionalized N‐Heterocyclic Carbene Ruthenium Complexes

European Journal of Inorganic Chemistry, 2023
AbstractA catalytic system for the direct β‐alkylation of secondary alcohol with primary alcohol has been investigated. In this work, a series of cationic Ru(II)(η6‐p‐cymene) complexes with thioether‐functionalized N‐heterocyclic carbene ligands (imidazole‐based 1 a–l and benzimidazole‐based 2 a–e) have been successfully synthesized and evaluated as ...
Victoria Mechrouk, Aline Maisse‐François, Stéphane Bellemin‐Laponnaz, Thierry Achard   +3 more
openaire   +2 more sources

Efficient and Practical Transfer Hydrogenation of Ketones Catalyzed by a Simple Bidentate Mn−NHC Complex [PDF]

, 2019
Catalytic reductions of carbonyl‐containing compounds are highly important for the safe, sustainable, and economical production of alcohols. Herein, we report on the efficient transfer hydrogenation of ketones catalyzed by a highly potent Mn(I)−NHC ...
Benschop, Joeri, Filonenko, Georgy A., Munck, Vincent J. de, Müller, Christian, Pidko, Evgeny A., Putten, Robbert van, Weber, Manuela   +6 more
core   +1 more source

Asymmetric addition of chiral boron-ate complexes to cyclic iminium ions [PDF]

, 2014
Boron-ate complexes derived from enantioenriched secondary benzylic boronic esters and aryl lithiums have been reacted with quinolinium, pyridinium and dihydroisoquinolinium salts to give enantioenriched heterocyclic structures with very high ...
Aggarwal, Varinder K., Feeney, Katie M J, Leonori, Daniele, Mohiti, Maziar, Rampalakos, Konstantinos   +4 more
core   +2 more sources

Asymmetric Synthesis of 1-Heteroaryl-1-arylalkyl Tertiary Alcohols and 1-Pyridyl-1-arylethanes by Lithiation-Borylation Methodology [PDF]

, 2013
The synthesis of highly enantioenriched alpha-heterocyclic tertiary alcohols has been achieved via lithiation-borylation of a configurationally stable lithiated carbamate and heterocyclic pinacol boronic esters followed by oxidation. Protodeboronation of
Aggarwal V. K., Biradar D. B., Biradar D. B., Carstens A., Charlotte G. Watson, Chen C.-A., Cozzi P. G., Dosa P. I., García C., García C., García C., Garg D. C., Greene M. A., Hatano M., Hatano M., Hatano M., Hoppe D., Hu Q., Kanai M., Luderer M. R., Madduri A. V. R., Madduri A. V. R., Maity P., Matsunaga N., Messaoudi S., Moree W. J., Nave S., Ou L., Pathak T. P., Ramón D. J., Ramón D. J., Shi S.-L, Shibasaki M., Song S., Starck J. P., Stymiest J. L., Taylor B. L. H., Varinder K. Aggarwal, Wada R., Weber B., Yus M., Yus M.   +41 more
core   +3 more sources