Changes in the intestinal microbiota after a short period of dietary over-indulgence, representative of a holiday or festival season [PDF]
, 2008 The effects on the intestinal microbiota of a short period of marginal over-eating, characteristic of holiday or festival periods, were investigated in a pilot study.
Gougoulias, Christos +5 more
core
Analysis of the Cramer classification scheme for oral systemic toxicity - implications for its implementation in Toxtree [PDF]
, 2011 In the application of the Threshold of Toxicological Concern (TTC) concept to non-cancer endpoints, the decision tree proposed by Cramer, Ford and Hall in 1978, commonly referred to as the Cramer scheme, is probably the most widely used approach for ...
LAPENNA SILVIA, WORTH Andrew
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Characterization of craft beer through flavour component analysis by GC-MS and multivariate statistical tools [PDF]
, 2018 Beer is a rather popular drink and represents the most widely consumed alcoholic beverage in the world.The present research aims at characterizing the flavour profile of lager pilsner, the category of low fermentation beers most common in Europe.
Boccacci Mariani Maurizio +2 more
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A steric tethering approach enables palladium-catalysed C-H activation of primary amino alcohols. [PDF]
, 2015 Aliphatic primary amines are a class of chemical feedstock essential to the synthesis of higher-order nitrogen-containing molecules, commonly found in biologically active compounds and pharmaceutical agents.
A McNally +52 more
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Enantioselective synthesis of (+)-petromyroxol, enabled by rhodium-catalyzed denitrogenation and rearrangement of a 1-sulfonyl-1,2,3-triazole [PDF]
, 2015 Petromyroxol is a non-racemic mixture of enantiomeric oxylipids isolated from water conditioned with larval sea lamprey. The (+)-antipode exhibits interesting biological properties but only 1 mg was isolated from >100000 L of water.
Boyer, Alistair
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Remodelling of the natural product fumagillol employing a reaction discovery approach [PDF]
, 2011 In the search for new biologically active molecules, diversity-oriented synthetic strategies break through the limitation of traditional library synthesis by sampling new chemical space. Many natural products can be regarded as intriguing starting points
Balthaser, Bradley R. +4 more
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Synthetic chemistry and biological activity of pentafluorosulphanyl (SF5) organic molecules [PDF]
, 2012 Acknowledgements We thank the European Commission for financial support (Industry Academia Partnerships and Pathways project “PET BRAIN”, Contract No 251482). S.A.
Altomonte, Stefano, Zanda, Matteo
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[Chiroptical study of O-heterocyclic compounds, secondary mono-alcohols and primary monoamines].
Acta pharmaceutica Hungarica, 2004 Starting from cholesterol (1), model compounds containing 2,3-dihydrobenzo[b]furan or 4H-benzopyran chromophores of known configurations and rigid conformations (6, 10 and 7) were synthesized in a stereocontrolled sequence. A helicity rule was established for the 2,3-dihydrobenzo[b]furan chromophore (P/M helicity of the heteroring gives rise to ...
Tibor, Kurtán, Sándor, Antus
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A Simple Nickel Catalyst Enabling an E‐Selective Alkyne Semihydrogenation [PDF]
, 2019 Stereoselective alkyne semihydrogenations are attractive approaches to alkenes, which are key building blocks for synthesis. With regards to the most atom economic reducing agent dihydrogen (H 2 ), only few catalysts for the challenging E ‐selective ...
Kaewmee, Benyapa +3 more
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Dirhenium Carbonyl Complexes Bearing 2-Vinylpyridine, Morpholine and 1-Methylimidazole Ligands [PDF]
, 2008 Treatment of the labile compound [Re2(CO)8(MeCN)2] with 2-vinylpyridine in refluxing benzene affords exclusively the new compound [Re2(CO)8(μ-η1:η2-NC5H4CHCH2)] (1) in 39% yield in which the μ-η1:η2-vinylpyridine ligand is coordinated to one Re atom ...
Ahmed, Faruque +7 more
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