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Surgical Management of Secondary Hyperparathyroidism [PDF]
Secondary hyperparathyroidism (SHPT) affects a majority of patients with chronic kidney disease (CKD) of stage 3 or worse. Despite the development of calcimimetics and their effectiveness in treating SHPT, many patients continue to fail medical ...
Gabrielle K. Steinl, Jennifer H. Kuo
doaj +5 more sources
Mechanism of calcitriol regulating parathyroid cells in secondary hyperparathyroidism
A common consequence of chronic renal disease is secondary hyperparathyroidism (SHPT) and is closely related to the mortality and morbidity of uremia patients.
Zeli Xiang+4 more
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Secondary hyperparathyroidism is a complex pathology that develops as chronic kidney disease progresses. The retention of phosphorus and the reductions in calcium and vitamin D levels stimulate the synthesis and secretion of parathyroid hormone as well ...
María E. Rodríguez-Ortiz+1 more
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Parathyroidectomy in the Management of Secondary Hyperparathyroidism
Secondary hyperparathyroidism develops in CKD due to a combination of vitamin D deficiency, hypocalcemia, and hyperphosphatemia, and it exists in nearly all patients at the time of dialysis initiation. There is insufficient data on whether to prefer vitamin D analogs compared with calcimimetics, but the available evidence suggests advantages with ...
Lau, Wei Ling+2 more
openaire +6 more sources
Bradycardia secondary to primary hyperparathyroidism [PDF]
Clinical doctors rarely associate hyperparathyroidism with significant bradyarrhythmia. We report a rare case of a patient initially misdiagnosed with primary sick sinus syndrome, which was eventually shown to be secondary to primary hyperparathyroidism.
Fei Liu+3 more
doaj +3 more sources
Secondary hyperparathyroidism (SHPT) does not initiate as a primary dysfunction of parathyroid glands resulting from an intrinsic defect or disease but is the physiologic response of parathyroids to metabolic changes elsewhere in the body occurring over time.
Muppidi V, Meegada SR, Rehman A.
europepmc +3 more sources
Secondary Hyperparathyroidism in Chronic Kidney Disease: Pathophysiology and Management
Serum calcium concentration is the main determinant of parathyroid hormone (PTH) release. Defect in the activation of vitamin D in the kidneys due to chronic kidney disease (CKD) leads to hypocalcemia and hyperphosphatemia, resulting in a compensatory ...
Elmukhtar M. Habas+3 more
semanticscholar +1 more source
Secondary hyperparathyroidism and adverse health outcomes in adults with chronic kidney disease
Background Secondary hyperparathyroidism (sHPT) develops frequently in patients with chronic kidney disease (CKD). However, the burden and long-term impact of sHPT on the risk of adverse health outcomes are not well studied.
Yang Xu+4 more
semanticscholar +1 more source
Objective: To develop evidence-based recommendations for safe, effective, and appropriate treatment of secondary (SHPT) and tertiary (THPT) renal hyperparathyroidism.
Sophie Y. Dream+9 more
semanticscholar +1 more source
Hypercalciuria and hyperparathyroidism — is there always a connection?
Hypercalciuria is a pathological condition characterized by an excess of daily calcium excretion. A high concentration of urine calcium can initiate stone formation. There are several types of hypercalciuria, each requires an individual approach.
S. S. Mirnaya, A. K. Eremkina
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