Results 1 to 10 of about 2,657,498 (292)

Recent advances in understanding and managing secondary hyperparathyroidism in chronic kidney disease [version 1; peer review: 3 approved]

F1000Research, 2020
Secondary hyperparathyroidism is a complex pathology that develops as chronic kidney disease progresses. The retention of phosphorus and the reductions in calcium and vitamin D levels stimulate the synthesis and secretion of parathyroid hormone as well ...
María E. Rodríguez-Ortiz, Mariano Rodríguez   +1 more
doaj   +2 more sources

Vitamin D Deficiency and Secondary Hyperparathyroidism in the Elderly: Consequences for Bone Loss and Fractures and Therapeutic Implications [PDF]

Endocrine reviews, 2001
Vitamin D deficiency is common in the elderly, especially in the housebound and in geriatric patients. The establishment of strict diagnostic criteria is hampered by differences in assay methods for 25-hydroxyvitamin D. The synthesis of vitamin D3 in the
Paul Lips
semanticscholar   +3 more sources

Secondary and Tertiary Hyperparathyroidism:A Narrative Review [PDF]

Scandinavian Journal of Surgery, 2020
End-stage renal disease is often complicated by the occurrence of secondary and eventually tertiary hyperparathyroidism, characterized by increased parathormone, calcium, and phosphate concentrations.
Kruijff, S., Noltes, M. E., van der Plas, W. Y., van Ginhoven, T. M.   +3 more
core   +2 more sources

Brown Tumour in a Patient with Secondary Hyperparathyroidism Resistant to Medical Therapy: Case Report on Successful Treatment after Subtotal Parathyroidectomy [PDF]

International Journal of Endocrinology, 2009
Brown tumour represents a serious complication of hyperparathyroidism. Differential diagnosis, based on histological examination, is only presumptive and clinical, radiological and laboratory data are necessary for definitive diagnosis. Here we describe
Nicola Di Daniele, Stefano Condò, Michele Ferrannini, Marta Bertoli, Valentina Rovella, Laura Di Renzo, Antonino De Lorenzo   +6 more
doaj   +4 more sources

Secondary Hyperparathyroidism in Chronic Kidney Disease: Pathophysiology and Management

Cureus, 2021
Serum calcium concentration is the main determinant of parathyroid hormone (PTH) release. Defect in the activation of vitamin D in the kidneys due to chronic kidney disease (CKD) leads to hypocalcemia and hyperphosphatemia, resulting in a compensatory ...
E. Habas, M. Eledrisi, F. Khan, Abdel-Naser Elzouki   +3 more
semanticscholar   +1 more source

Secondary hyperparathyroidism and adverse health outcomes in adults with chronic kidney disease

Clinical Kidney Journal, 2021
Background Secondary hyperparathyroidism (sHPT) develops frequently in patients with chronic kidney disease (CKD). However, the burden and long-term impact of sHPT on the risk of adverse health outcomes are not well studied.
Yang Xu, M. Evans, M. Soro, P. Bárány, J. Carrero   +4 more
semanticscholar   +1 more source

The American Association of Endocrine Surgeons Guidelines for the Definitive Surgical Management of Secondary and Tertiary Renal Hyperparathyroidism

Annals of Surgery, 2022
Objective: To develop evidence-based recommendations for safe, effective, and appropriate treatment of secondary (SHPT) and tertiary (THPT) renal hyperparathyroidism.
Sophie Y. Dream, L. Kuo, J. Kuo, S. Sprague, F. Nwariaku, M. Wolf, J. Olson, S. Moe, Brenessa Lindeman, Herbert Chen   +9 more
semanticscholar   +1 more source

Secondary hyperparathyroidism, weight loss, and longer term mortality in haemodialysis patients: results from the DOPPS

Journal of Cachexia, Sarcopenia and Muscle, 2021
Wasting is a common complication of kidney failure that leads to weight loss and poor outcomes. Recent experimental data identified parathyroid hormone (PTH) as a driver of adipose tissue browning and wasting, but little is known about the relations ...
H. Komaba, Junhui Zhao, Suguru Yamamoto, T. Nomura, D. Fuller, K. McCullough, P. Evenepoel, A. Christensson, Xinju Zhao, M. Alrukhaimi, Fadwa Al-Ali, E. Young, B. Robinson, M. Fukagawa   +13 more
semanticscholar   +1 more source

Hypercalciuria and hyperparathyroidism — is there always a connection?

Ожирение и метаболизм, 2022
Hypercalciuria is a pathological condition characterized by an excess of daily calcium excretion. A high concentration of urine calcium can initiate stone formation. There are several types of hypercalciuria, each requires an individual approach.
S. S. Mirnaya, A. K. Eremkina
doaj   +1 more source

Mechanism of calcitriol regulating parathyroid cells in secondary hyperparathyroidism

Frontiers in Pharmacology, 2022
A common consequence of chronic renal disease is secondary hyperparathyroidism (SHPT) and is closely related to the mortality and morbidity of uremia patients.
Zeli Xiang, Ming Wang, Changxiu Miao, Die Jin, Hongyue Wang   +4 more
doaj   +1 more source