Predictors of Mortality in Patients With Multiple Endocrine Neoplasia Type 1
SUMMARY Objective Multiple Endocrine Neoplasia Type 1 (MEN 1) is an autosomal dominant disease predisposing to hyperplasia and neoplasia in diverse endocrine tissues. Patients typically present with endocrine abnormalities before the age of 30 years and have reduced life expectancy.
Jasmine J. Zhu, John R Burgess
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ABSTRACT Introduction Cardiovascular disease remains the primary cause of mortality after kidney transplantation. Hyperparathyroidism (HPT) may contribute to the accelerated progression of coronary artery disease (CAD) and peripheral artery disease (PAD), particularly in transplant patients.
Lane T. Cavey+7 more
wiley +1 more source
Molecular mechanism for transcriptional regulation of the parathyroid hormone gene by Epiprofin
The secretion of parathyroid hormone (PTH) from the chief cells in the parathyroid glands is regulated by the concentration of extracellular calcium. Epiprofin (Epfn) expression is induced by NFATc2 in response to elevated serum calcium, and Epfn negatively regulates PTH production.
Takashi Nakamura+8 more
wiley +1 more source
Secondary hyperparathyroidism downregulates lipoprotein lipase expression in chronic renal failure [PDF]
Nosratola D. Vaziri+2 more
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Melatonin: A Potential Therapy for Osteoporosis With Insights Into Molecular Mechanisms
ABSTRACT Melatonin is a versatile neurohormone with diverse molecular functions, including sleep regulation, inflammation reduction, antioxidant activity, immune modulation, and anticancer properties. In bone metabolism, it promotes osteoblast formation, inhibits osteoclast activity, and synchronizes skeletal tissue rhythms to support bone health.
Ko‐Hsiu Lu+4 more
wiley +1 more source
Aggressive jaw brown tumor in a 28-year-old man with long-lasted chronic kidney disease [PDF]
Brown tumors are bony lesions triggered by rapid osteoclastic activity, which rarely involved jaws (1-3). In fact brown tumors or osteoclastomas are erosive bony lesions appearing as a complication of hyperparathyroidism.
Ardalan, Mohammadreza.+5 more
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Localization of ectopic parathyroid tissue: usefulness of <sup>99m</sup>Tc sestamibi scanning in a dialysis patient with severe secondary hyperparathyroidism [PDF]
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ABSTRACT Background The effects of vitamin D supplementation are unknown in dogs with protein‐losing enteropathy (PLE). Objective To evaluate the safety, efficacy, and clinical benefit of orally administered cholecalciferol in dogs with PLE and decreased serum concentrations of 25OHD.
Sara A. Jablonski+6 more
wiley +1 more source
Kidney transplantation. Modern trends in kidney transplantation. [PDF]
Trends in renal transplantation stem from recognition of the virtues and drawbacks of this kind of treatment and from a better appreciation of the interrelationship between transplantation and ...
Putnam, CW, Starzl, TE, Weil, R
core
Secondary Hyperparathyroidism in a Patient with Eight Parathyroid Glands [PDF]
O. Joe Hines, H. Earl Gordon
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