Results 291 to 300 of about 4,368,112 (356)

Trends in first‐line monotherapy and combination therapy for hypertension in UK primary care

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Debate remains about the optimal initial treatment strategy for hypertension. Most guidelines recommend first‐line combination therapy for most patients. However, the UK's National Institute for Health and Care Excellence recommends first‐line monotherapy for all patients.
Kyle Johnson   +4 more
wiley   +1 more source

Availability, use, efficacy and safety of bevacizumab in European hereditary haemorrhagic telangiectasia centres

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Introduction Bevacizumab, a vascular endothelial growth factor inhibitor, is used off‐label for treatment of severe anaemia related to epistaxis, gastrointestinal bleeding and/or severe hepatic arteriovenous malformations (HAVM) and right‐sided cardiac failure in patients with hereditary haemorrhagic telangiectasia (HHT).
Pernille D. Haahr   +18 more
wiley   +1 more source

Development and Implementation of a Dynamically Updated Big Data Intelligence Platform Using Electronic Medical Records for Secondary Hypertension. [PDF]

open access: yesRev Cardiovasc Med
Li N   +13 more
europepmc   +1 more source

GLP‐1 agonist‐associated presentations to unscheduled care: An opportunistic pilot study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
The impact of GLP‐1 or GIP/GLP‐1 receptor agonist use on unscheduled care is not well‐described. We conducted a prospective, observational study using opportunistic screening by clinicians as a first step to understanding the effect of GLP‐1 or GIP/GLP‐1 agonists on Emergency Department presentations and to guide future studies.
Oliver Thomas, James Michael Coulson
wiley   +1 more source

A Core Head, Neck, and Neuroanatomy Syllabus for Physical Therapy Student Education

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Head, neck, and neuroanatomy are essential components of physical therapy education due to their broad clinical applications. Detailed syllabi exist for medical students, yet none have been developed for physical therapy. This study aimed to produce an International Federation of Associations of Anatomists core head, neck, and neuroanatomy ...
Stephanie J. Woodley   +4 more
wiley   +1 more source

Efficacy and safety of combining bevacizumab and fractionated stereotactic radiotherapy for extensive brain metastases in patients with non‐small cell lung cancer: a prospective phase II study (GASTO‐1053)

open access: yesCancer Communications, EarlyView.
Abstract Background The prognosis for non‐small cell lung cancer (NSCLC) patients with extensive brain metastases (BMs) treated with radiotherapy alone remains poor. Based on the synergistic potential of radiotherapy and angiogenesis inhibitors, we initiated this phase II study to assess the efficacy and safety of combining bevacizumab (Bev) with ...
Rui Zhou   +16 more
wiley   +1 more source

Crestal approach for repair of oroantral bone defects and subsequent implant placement

open access: yesClinical Advances in Periodontics, EarlyView.
Abstract Background Oroantral communication (OAC) can occur after a dental extraction. Occasionally, bony defects may persist despite successful soft tissue closure of the OAC. The absence of bone in these areas poses challenges for dental implant placement.
Min Yang   +3 more
wiley   +1 more source

Sleep Apnea: Secondary Cause or Risk Factor for Hypertension?

open access: green, 2012
Costas Thomopoulos   +3 more
openalex   +2 more sources

Endothelium‐Independent Relaxation of Alkaloid Boldine in Isolated Aortas From Normotensive and Hypertensive Rats: Participation of Ca2+ Channels

open access: yesChemistry &Biodiversity, EarlyView.
Involvement of Ca2+ channels in boldine‐induced vascular relaxation. ABSTRACT The regulation of vascular tone plays a fundamental role in blood pressure homeostasis and still represents a significant challenge in clinical practice. Boldine, a naturally occurring alkaloid from Peumus boldus, has emerged as a compound of interest due to its therapeutic ...
Martina Odebrecht Cavichiolo   +3 more
wiley   +1 more source

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