Results 61 to 70 of about 7,366,504 (288)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Nano-Scale Secondary Ion Mass Spectrometry: A Paradigm Shift in Soil Science

Journal of Spectroscopy
Soils exhibit structural heterogeneity across diverse spatio-temporal scales, yielding myriad of microhabitats, highlighting the need for a nuanced understanding of the intricate interactions within the soil matrix.
Yasir Hanif Mir, Anzhen Qin, Shakeel Mir, Shafeeq Ur Rahman, Mehnaza Mushtaq, Mumtaz A. Ganie, M. H. Chesti, Javid A. Bhat, Zahoor A. Baba, M. Auyoub Bhat, Inayat M. Khan, Rehana Rasool, Aanisa Manzoor Shah, Shazia Sadiq, Syed Mohammed Basheeruddin Asdaq, Mohammad Javed Ansari, Ghulam Yasin   +16 more
doaj   +1 more source

Lipid mapping in human dystrophic muscle by cluster-time-of-flight secondary ion mass spectrometry imaging

Journal of Lipid Research, 2008
Human striated muscle samples, from male control and Duchenne muscular dystrophy-affected children, were subjected to cluster-time-of-flight secondary ion mass spectrometry (cluster-ToF-SIMS) imaging using a 25 keV Bi3+ liquid metal ion gun under static ...
Nora Tahallah, Alain Brunelle, Sabine De La Porte, Olivier Laprévote   +3 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Influence of support material on formation of electrocatalytic thin films - a secondary ion mass spectrometry study

, 1997
The influence of various support materials, such as nickel and titanium, on the structure of TiO 2, RuO 2, RuO 2/TiO 2 and IrO 2/ TiO2 electrocatalytic thin films was investigated in detail by secondary ion mass spectrometry (SIMS).
S Daolio, B Facchin, M Fabrizio, J Kristóf, J Mihály, C Piccirillo   +5 more
core   +2 more sources

Degrees of freedom effect on fragmentation in tandem mass spectrometry of singly charged supramolecular aggregates of sodium sulfonates [PDF]

, 2013
The characteristic collision energy (CCE) to obtain 50% fragmentation of positively and negatively single charged non-covalent clusters has been measured.
TURCO LIVERI, Vincenzo, Indelicato, S, Drahos, László, Liveri, Vincenzo Turco, Drahos, L, TuriàK, L, Indelicato, Serena, Vèkey, K, Vékey, Károly, Turiák, Lilla, Bongiorno, David, Indelicato, Sergio, Ceraulo, Leopoldo   +12 more
core   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Linking biogenic hydrocarbons to biogenic aerosol in the Borneo rainforest [PDF]

Atmospheric Chemistry and Physics, 2013
Emissions of biogenic volatile organic compounds are though to contribute significantly to secondary organic aerosol formation in the tropics, but understanding these transformation processes has proved difficult, due to the complexity of the chemistry ...
J. F. Hamilton, M. R. Alfarra, N. Robinson, M. W. Ward, A. C. Lewis, G. B. McFiggans, H. Coe, J. D. Allan   +7 more
doaj   +1 more source

Performance of a corona ion source for measurement of sulfuric acid by chemical ionization mass spectrometry [PDF]

, 2010
The performance of an ion source based on corona discharge has been studied. This source is used for the detection of gaseous sulfuric acid by chemical ionization mass spectrometry (CIMS) through the reaction of NO−3 ions with H2SO4.
Rondo, L, Ehrhart, Sebastian, Curtius, Joachim, A. Kürten, Rondo, Linda, L. Rondo, Kürten, Christoph Andreas, J. Curtius, Curtius, J, S. Ehrhart, Ehrhart, S, Kürten, A   +11 more
core   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source