Results 111 to 120 of about 1,354,653 (354)

Additional file 14 of Multi-omics analyses revealed key factors involved in fluorescent carbon-dots-regulated secondary metabolism in Tetrastigma hemsleyanum

, 2022
Xin Peng, Zhuomi Xie, Xiuhua Wang, Yuxiang Zhao, Chuyun Yang, Zhongyi Zhang, Mingjie Li, Jianping Zheng, Yuhui Wang   +8 more
openalex   +1 more source

BMQ [PDF]

, 1963
BMQ: Boston Medical Quarterly was published from 1950-1966 by the Boston University School of Medicine and the Massachusetts Memorial ...
Antuna, Juan, Bagnoli, Thomas, Barber, Doris E., Cocchiarella, John P., Duke, Martin, Estes, J. Worth, Friedlander, Walter J., Goldsmith, Harry S., Gooding, Gretchen W., Goofman, Max L., Haseotes, Hytho V., Hass, Gerald, Hastings, A. Baird, Jackson, David R., Johnson, David S., Kechejian, Sarkis J., Kramer, Philip, Litman, George I., Madoff, Irving M., McLellan, Patricia A., O'Hara, Vincent S., Peabody, C. Newton, Pryles, Charles V., Small, Donald M., Tedeschi, Luke G., Walker, Sydney, III   +25 more
core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Development of an RNA Nanostructure for Effective Botrytis cinerea Control through Spray-Induced Gene Silencing without an Extra Nanocarrier

Journal of Fungi
Spray-induced gene silencing represents an eco-friendly approach for crop protection through the use of double-stranded RNA (dsRNA) to activate the RNA interference (RNAi) pathway, thereby silencing crucial genes in pathogens.
Fangli Wu, Ling Yan, Xiayang Zhao, Chongrun Lv, Weibo Jin   +4 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Comparative Genomics and Phylogenetic Analyses of Aquarius macrophyllus and Related Genera in Alismataceae Based on Plastome Data

Ecology and Evolution
Aquarius macrophyllus, an aquatic species native to South America, has been widely utilized as an ornamental plant. Although the plastome data have been commonly used in plant evolution and phylogenetics, research on the plastome of A.
Jie Li, Shengnan Wei, Jianan Ying, Qixiang Lu   +3 more
doaj   +1 more source

Development of Triangle RNA Nanostructure for Enhancing RNAi-Mediated Control of Botrytis cinerea Through Spray-Induced Gene Silencing Without Extra Nanocarrier

Biology
Botrytis cinerea, a necrotrophic fungal pathogen responsible for gray mold, poses a severe threat to over 1400 plant species, causing significant pre- and postharvest losses worldwide.
Ya Chen, Yiqing Liu, Yani Huang, Fangli Wu, Weibo Jin   +4 more
doaj   +1 more source

Effects of mrpigG on Development and Secondary Metabolism of Monascus ruber M7 [PDF]

, 2020
Li Li, Fusheng Chen
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Evolution and regulation of microbial secondary metabolism [PDF]

, 2020
Guillem Santamaria, Chen Liao, Zhe Wang, Kyu Y. Rhee, Francisco Pinto, Jinyuan Yan, João B. Xavier   +6 more
openalex   +1 more source