Results 91 to 100 of about 219,209 (310)

Vm–MSI: a Vancomycin–Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum

Advanced Science, EarlyView.
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li, Kang Wang, Wenzhuang Shi, Xu Wang, Duxin Li, Yanli Liu, Peng Zhang, Yipeng Wang   +7 more
wiley   +1 more source

Tissue‐Resident Macrophage‐Derived E3 Ligase SMURF2 Restricts Autoimmune Inflammation by Mediating the Degradation of p‐TBK1

Advanced Science, EarlyView.
Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An, Jun Li, Lingling Wang, Chengyuan Li, Zhenpeng Jin, Yushi Yao, Minmin Jiang, Wenlong Lin, Xiaojian Wang   +8 more
wiley   +1 more source

Inner cover, Editor, Contents

International Journal of Secondary Metabolite, 2017
Dear Readers, [1] Our Journal has been published two issues (January and July) in each year since 2014. Volume 4, Number 1 issue is now available on the website of the journal.
Ramazan MAMMADOV
doaj  

Targeting Adipose Tissue Function Protects Against Heart Failure with Preserved Ejection Fraction

Advanced Science, EarlyView.
This study explores the role adipose tissue (AT) phenotypes have in determining cardiovascular outcomes in an obesity‐related heart failure with preserved ejection fraction (HFpEF) model. Pharmacological induction of thermogenesis promoted resilience to HFpEF‐induced remodeling of AT and conferred cardioprotection. Surgical and genetic models confirmed
Jordan Jousma, Zhenbo Han, Jooman Park, Gege Yan, Sen Zhang, Youjeong Kwon, Sarath Babu Nukala, Jindpreet Kandola, Sandra Pinho, Chong Wee Liew, Yuwei Jiang, Sang‐Ging Ong   +11 more
wiley   +1 more source

CONTENT OF SECONDARY METABOLITES WITH INSECTICIDAL AND REPELLENT ACTIVITY IN THE ALCOHOLIC EXTRACT AND ESSENTIAL OIL OF CHAEROPHYLLUM AROMATICUM L.

International Journal of Secondary Metabolite, 2016
The most of plant secondary metaboliteshave a safety function to protect plants from pathogens and herbivorous. The important role in the protection of plants from insect pests plays terpenoids and their derivatives.We studied the ...
N. V. VORONOVA
doaj  

Comparative assessment of antioxidant activity in red apricot (Prunus armeniaca L.) and Fig fruits (Ficus carica L.) cultivated in Nakhchivan AR, Azerbaijan

International Journal of Secondary Metabolite
Red apricot (Prunus spp.) and Black Fig (Ficus carica L.) are two of the most commonly grown summer fruits in the Nakhchivan region. In this preliminary study, ethanol fruit extracts were compared based on their total phenolic content (TPC) and ...
Azize Huseynova, Elsevar Asadov, Sura Rahimova   +2 more
doaj   +1 more source

A Soft Spot for Chemistry–Current Taxonomic and Evolutionary Implications of Sponge Secondary Metabolite Distribution [PDF]

, 2021
Adrian Galitz, Yoichi Nakao, Peter J. Schupp, Gert Wörheide, Dirk Erpenbeck   +4 more
openalex   +1 more source

2‐line Ferrihydrite Enhance Microbial Synthesis of Plant Biostimulants in Composted Biosolid by Regulating Phyla Pseudomonadota and Actinomycetota

Advanced Science, EarlyView.
This study explores how iron and manganese oxides transform sewage sludge into plant biostimulants during composting. Non‐targeted identification reveals the main species of plant biostimulants. Metagenomic analysis reveals that 2‐line ferrihydrite specifically enriches microbial genes for biosynthesis, boosting plant‐growth promoters.
Yu Zhang, Ziwei Zhang, Zexu Chen, Boyuan Yang, Siying Cai, Jun Chen, Jianhua Guo, Weijun Zhang   +7 more
wiley   +1 more source

The Conjugates of Phenolic Acids in Lichens of the Order Lecanorales

International Journal of Secondary Metabolite, 2016
Lichens are symbiotic associations of a fungus (usually an ascomycete) and a photobiont, which may be an alga and/or a cyanobacterium. Lichens dominate on about 6–8% of land surface, mainly in the habitats with severe climatic conditions.
T. N. NIKOLAEVA, P. V. LAPSHIN, A. G. ZAVARZINA, N. V. ZAGOSKINA   +3 more
doaj  

Salicylic acid effects on some physiochemical properties and secondary metabolite accumulation in Mentha piperita L. under water deficit stress

, 2020
Gholamreza Abdi, Lila Karami
openalex   +1 more source