Results 81 to 90 of about 215,278 (261)

CONTENT OF SECONDARY METABOLITES WITH INSECTICIDAL AND REPELLENT ACTIVITY IN THE ALCOHOLIC EXTRACT AND ESSENTIAL OIL OF CHAEROPHYLLUM AROMATICUM L.

International Journal of Secondary Metabolite, 2016
The most of plant secondary metaboliteshave a safety function to protect plants from pathogens and herbivorous. The important role in the protection of plants from insect pests plays terpenoids and their derivatives.We studied the ...
N. V. VORONOVA
doaj  

Comparative assessment of antioxidant activity in red apricot (Prunus armeniaca L.) and Fig fruits (Ficus carica L.) cultivated in Nakhchivan AR, Azerbaijan

International Journal of Secondary Metabolite
Red apricot (Prunus spp.) and Black Fig (Ficus carica L.) are two of the most commonly grown summer fruits in the Nakhchivan region. In this preliminary study, ethanol fruit extracts were compared based on their total phenolic content (TPC) and ...
Azize Huseynova, Elsevar Asadov, Sura Rahimova   +2 more
doaj   +1 more source

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

Advanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source

The Conjugates of Phenolic Acids in Lichens of the Order Lecanorales

International Journal of Secondary Metabolite, 2016
Lichens are symbiotic associations of a fungus (usually an ascomycete) and a photobiont, which may be an alga and/or a cyanobacterium. Lichens dominate on about 6–8% of land surface, mainly in the habitats with severe climatic conditions.
T. N. NIKOLAEVA, P. V. LAPSHIN, A. G. ZAVARZINA, N. V. ZAGOSKINA   +3 more
doaj  

Time‐Controlled Refrigerated Stem Cell Therapy Mitigates Scleroderma Fibrosis via Modulation of Mitochondrial Autophagy and Gut Metabolism

Advanced Science, EarlyView.
This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia, Chenfei Kong, Xiaoming Zhao, Naixu Shi, Jinlan Jiang, Ping Li   +5 more
wiley   +1 more source

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao, Jun Wang, Hanwenchen Wang, Xiang Sun, Fang Fang, Shiying Li, Jianping Liu, Changrong Shi, Pengyuan Qi, Jianhua Zou, Xiaoyuan Chen, Kailin Cai   +11 more
wiley   +1 more source

Phenolic Compounds of Fresh Roots and Rhizomes of Garden Angelica Angelica Archangelica L.

International Journal of Secondary Metabolite, 2014
Because in the process of drying and storage of plant materials is a change of genuine compounds, we studied the content of phenolic compounds in freshly drawn angelica roots and rhizomes of the drug Angelica archangelica L. samples had been taken on the
R. M. BASHIROVA, А. G. MUSTAFIN1, E. G. GALKIN, F. F. ABDULLAEV   +3 more
doaj  

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

Advanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang, Mengyu Zhang, Weipeng Gong, Jiaxuan Wu, Junping Zhang, Wenxiu Zhang, Yue Liu, Kui Wang, Canhua Huang, Jun Zhou, Sijin Wu, Yan Li, Tianliang Li   +12 more
wiley   +1 more source

Effect of Media on Gynogenesis Induction in Leek (allium ampeloprasum L.) Breeding Materials

International Journal of Secondary Metabolite, 2014
Leek (Allium ampeloprasum L.) is one of the economically important members of the genus Allium (family:Alliaceae). It is a self-compatible, outbreeding, tetraploid (2n=4X= 32) crop species that is very difficult to improve through traditional breeding ...
A. KASKA, F. CELEBI TOPRAK, A. R. ALAN   +2 more
doaj  

Epigenetic factors of the effect of UV-C and X-ray presowing seeds radiation exposure in Matricaria chamomilla L. genotypes

International Journal of Secondary Metabolite
In a series of experiments using both X-ray and UV-C radiation exposure a parallel study of several pharmacological characteristics of the Matricaria chamomilla L. genotype group was carried out.
Ludmila Hlushchenko, Vladyslav Zhuk, Alexandra Kravets, Daryna Sokolova   +3 more
doaj   +1 more source