Results 81 to 90 of about 3,054,813 (309)

Biosynthesis and function of secondary metabolites [PDF]

open access: yesBeilstein Journal of Organic Chemistry, 2011
Natural products have long been used by humans owing to their beneficial effects. Indulgences such as coffee and tea, with their moderate stimulatory properties, have a long cultural tradition and are today some of the most important agricultural products worldwide. Other drugs have much stronger impacts on the central nervous system. For example, coca
openaire   +3 more sources

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand   +5 more
wiley   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau   +11 more
wiley   +1 more source

The Study of the Chemical Composition of Essential Oils Mentha Piperita L. are Grown in Non-Chernozem Zone of Russia

open access: yesInternational Journal of Secondary Metabolite, 2014
By gas-liquid chromatography and mass spectrometry has been investigated the composition of essential oils and the change in the ontogenesis and exogenous effects on the plant Mentha piperita L. drugs retardant type.
L. SUSHKOVA   +3 more
doaj  

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali   +4 more
wiley   +1 more source

Molecular interactions of some phenolics with 2019-nCoV and related pathway elements

open access: yes, 2021
As of June 2021, the novel coronavirus disease (SARS-CoV-2) resulted in 180 million cases worldwide and resulted in the death of approximately 4 million people.
Sarıkürkçü, Cengiz   +7 more
core   +1 more source

Juvenile Huntington Disease With Cerebellar‐Predominant Atrophy Identified by Genome Sequencing

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Juvenile Huntington disease accounts for a small fraction of Huntington disease cases and is driven by the largest trinucleotide repeat expansions. We describe a 6‐year‐old boy with progressive global regression, generalized dystonia, and epilepsy, in whom serial imaging showed striking cerebellar‐predominant atrophy with an initially normal ...
Enrique Gonzalez Saez‐Diez   +5 more
wiley   +1 more source

Comparison of Some Extraction Methods for Isolation of Catechins and Caffeine from Turkish Green Tea

open access: yesInternational Journal of Secondary Metabolite, 2015
Effective extraction of anticancer and antioxidant principles from Turkish green tea were main purpose of this work. The pre-optimized experimental condition for liquid extraction was employed for comparative appraisal.
Ezgi DEMİR   +2 more
doaj   +1 more source

The importance of Lavandula stoechas L. in pharmacognosy and phytotherapy

open access: yes, 2022
Lavandula stoechas is distributed in Africa, Europe, and Asia continents, especially in the countries of Southern Europe and North Africa neighboring the Mediterranean. The use of L.
Sarıkürkçü, Cengiz   +7 more
core   +1 more source

Single‐Cell Resolution Mapping of Osteoarthritis‐Associated Chondrocyte Dynamics Using a High‐Density CMOS MEA Platform

open access: yesAdvanced Healthcare Materials, EarlyView.
Single‐cell and spatially resolved impedance mapping using a high‐density CMOS‐MEA platform enables non‐invasive monitoring of osteoarthritis‐associated chondrocyte dynamics. Continuous label‐free measurements reveal heterogeneous remodeling behaviors, including proliferation, migration, and phenotypic transitions, establishing a powerful approach for ...
Neha Deshpande   +9 more
wiley   +1 more source

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