Results 121 to 130 of about 217,149 (260)

Assessing the impact of Djdi on the growth, nutrient uptake, and secondary metabolite production in Eruca vesicaria (L.) Cav. [PDF]

BMC Plant Biol
Ammar EE, Khalaf BM, Shaalan MAA, Gelany A, Elsherif DE.   +4 more
europepmc   +1 more source

Spatiotemporal Targeting Randle Cycle and Immune Checkpoint for Potent Antitumor Therapy

Advanced Science, EarlyView.
A glucose oxidase‐based nanogel (GOX‐NG) system using catechol‐functionalized alginate, exhibits enhanced tumor penetration, prolonged retention, and sustained glucose depletion in the tumor microenvironment. When combined with a fatty acid oxidation inhibitor, it implements dual metabolic suppression, thereby enhancing ROS‐induced immunogenic cell ...
Yuan Gao, Zijian Gong, Yixuan Fu, Jianan Zheng, Xiao Sang, Binglin Chen, Qinzhi Su, Weiping Gao, Fei Duan, Jinqi Wei, Xuliang Deng, Xinyu Liu   +11 more
wiley   +1 more source

Editorial: Modern cultivation techniques for medicinal plants: impact on yield and secondary metabolite production. [PDF]

Front Plant Sci
Radman S, Nicola S, Kacjan-Marsic N, Hazrati S.   +3 more
europepmc   +1 more source

NAD+ Metabolism Licenses Zygotic Genome Activation via PARP7‐Mediated ADP‐Ribosylation of UHRF1 in Mouse Early Embryos

Advanced Science, EarlyView.
This study uncovers a metabolic‐epigenetic axis licensing zygotic genome activation (ZGA) in mouse embryos. A developmental decline in NAD+ levels activates PARP7, which mono‐ADP‐ribosylates and stabilizes UHRF1. This modification promotes the establishment of permissive histone acetylation marks, thereby facilitating timely ZGA.
Guangyi Cao, Ziqi Zhang, Anqi Chen, Yanbo Liu, Yuling Lin, Lina Yu, Ruixin Shi, Aolei Guo, Yan Mao, Ganggui Lou, Chaojun Li, Luhong Wen, Guijun Yan, Haixiang Sun   +13 more
wiley   +1 more source

Response of the Arabidopsis indolic secondary metabolite network to infection with <i>Colletotrichum higginsianum</i>. [PDF]

Front Fungal Biol
Seufer J, Speer D, Aus den Erlen R, Glawischnig E, Voll LM.   +4 more
europepmc   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Secondary metabolites from mushrooms [PDF]

The Journal of Antibiotics, 2020
openaire   +2 more sources

Grape Pomace as a Platform for Secondary Metabolite Recovery: Mechanistic Insights into Bioactivity, Processing, and Functional Valorization. [PDF]

Foods
Trif M, Socol CT, Suciu MD, Rusu AV, Criste FL, Rus D, Bîtea C, Hossain MB, Ahmed L.   +8 more
europepmc   +1 more source

A Single‐Cell Transcriptomic Atlas of the Ovine Rumen Microbiome Characterizes Lineage‐Specific Metabolic Shifts Associated with Host Heat Tolerance

Advanced Science, EarlyView.
An optimized single‐cell transcriptomic framework profiles over 60 000 cells to map the ovine rumen microbiome, partitioning the ecosystem into seven cross‐species functional clusters. In heat‐resistant hosts, a lineage‐specific metabolic shift in Anaerovibrio lipolyticus toward a highly glycolytic phenotype contributes to a “nutritional sparing ...
Sanbao Zhang, Qinyang Jiang, Junjie Ma, Jianwei Zou, Fan Wang, Feifei Lv, Yanna Huang, Yongcheng Wang, Ziye Xu   +8 more
wiley   +1 more source

Unlocking the potential of endophytes in enhancing plant secondary metabolite biosynthesis. [PDF]

Biochem Biophys Rep
Alum EU, Nwuruku OA, Uti DE, Echegu DA, Ugwu OP, Egba SI, Agu PC, Aja PM.   +7 more
europepmc   +1 more source