Results 141 to 150 of about 219,209 (310)

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source

Unlocking the potential of endophytes in enhancing plant secondary metabolite biosynthesis. [PDF]

Biochem Biophys Rep
Alum EU, Nwuruku OA, Uti DE, Echegu DA, Ugwu OP, Egba SI, Agu PC, Aja PM.   +7 more
europepmc   +1 more source

Advances in understanding the functions and regulatory factors of secondary metabolites in Reynoutria japonica

Yanli Zhang, Jiaxing Huang, Jianhui Jia, Jiayan Jiang, Xinyan Ma, Lili Zhao, Yunrong Jing   +6 more
openalex   +1 more source

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source

Unveiling Valuable Secondary Metabolites from the Bioconversion of Banana ( Musa balbisiana ) Peel-Derived Biomass with Aspergillus niger . Metabolomic Insights into the Chemical Profiles

Jhuly Wellen Ferreira Lacerda, Giovanna Amaral Filipe, Lucas Pradi, Tatiane de Andrade Maranhão, Diogo Robl, Louis P. Sandjo   +5 more
openalex   +1 more source

PHYTOCHEMICAL SCREENING, QUANTITATIVE ANALYSIS OF PRIMARY AND SECONDARY METABOLITES OF ACACIA ARABICA BARK

, 2018
Mahendra A. Deshmukh, Madhuri A. Theng
openalex   +2 more sources

SECONDARY METABOLITES WITH ANTIBIOTIC ACTIVITY OF MARINE ACTINOBACTERIA

, 2021
K. S. Potapenko, Н. В. Коротаєва, V. O. Іvanytsia   +2 more
openalex   +2 more sources

Secondary Metabolites Produced by Macrophomina phaseolina Isolated from Eucalyptus globulus [PDF]

, 2020
Maria Michela Salvatore, Carina Félix, Fernanda Blauth de Lima, Vanessa Ferreira, Daniele Naviglio, Francesco Salvatore, Ana Sofia Duarte, Artur Alves, Anna Andolfi, Ana Cristina Esteves   +9 more
openalex   +1 more source

Two Novel S‐methyltransferases Confer Dimethylsulfide Production in Actinomycetota

Advanced Science, EarlyView.
This study identifies two novel S‐adenosine‐methionine‐dependent methyltransferases, MddM1 and MddM2, in actinomycetes from the Mariana Trench. These enzymes can convert toxic hydrogen sulfide (H2S) and methanethiol (MeSH) into dimethylsulfide (DMS), serving as a cellular detoxification and oxidative stress response.
Ruihong Guo, Zihua Guo, Yi Zhou, Yunhui Zhang, Haojin Cheng, Rebecca Devine, Chuang Sun, Ronghua Liu, Yanfen Zheng, Andrew J. Gates, Jonathan D. Todd, Xiao‐Hua Zhang   +11 more
wiley   +1 more source

Harnessing glycerol for secondary metabolite biosynthesis in microorganisms. [PDF]

World J Microbiol Biotechnol
Kamasaka K, Marcello L, Domingues L, Hasunuma T.   +3 more
europepmc   +1 more source