Results 241 to 250 of about 3,541,226 (351)

Gut Microbial Genetic Variation Prolongs Host Healthy Longevity and Remodels Metabolome and Proteome in Drosophila Melanogaster

Advanced Science, EarlyView.
This study reveals that specific genetic variations in gut‐residing Saccharomyces cerevisiae significantly extend healthspan and lifespan in Drosophila melanogaster. These mutants rejuvenate aged intestinal metabolism, upregulate mitochondrial proteins, and enhance energy pathways.
Liying Wang, Ziling Yang, Yulu Pang, Xinyue Wu, Xinrong Zhang, Tao Zhu, Xiaoyue Ding, Wei Liu, Yuan Zhou, Pengcheng Zhang, Ying Li, Zuobin Zhu   +11 more
wiley   +1 more source

Medicinal plants in a changing climate: understanding the links between environmental stress and secondary metabolite synthesis. [PDF]

Front Plant Sci
Jangpangi D, Patni B, Chandola V, Chandra S.   +3 more
europepmc   +1 more source

Genomic and Multi-Omics Analysis of Phlebopus portentosus: Effects of Cultivation on Secondary Metabolites [PDF]

Zihong Kang, Xiaolong Yuan, Chuanguang Zhang, Yi Wang, Lu Li, Yuan Zheng   +5 more
openalex   +1 more source

Herbivory-induced jasmonates constrain plant sugar accumulation and growth by antagonizing gibberellin signaling and not by promoting secondary metabolite production.

New Phytologist, 2017
R. A. Machado, I. Baldwin, Matthias Erb
semanticscholar   +1 more source

Deoxynivalenol Exposure Leads to Abnormal Renal Tubular Autophagy Flow

Advanced Science, EarlyView.
DON exposure disrupts the initiation of renal autophagy by inhibiting the formation of autophagosomes, thereby impairing mitochondrial degradation. Damaged mitochondria increase oxidative stress, reduce ferroptosis resistance, and cause lysosomal Fe2⁺ accumulation, further disrupting autophagy.
Hao Chen, Xintong Zhou, Jun Ma
wiley   +1 more source

Secondary Metabolites ofMiconia rubiginosa

, 2011
Juliana Rodrigues, Daniel Rinaldo, Marcelo Aparecido da Silva, Lourdes Campaner dos Santos, Wagner Vilegas   +4 more
openalex   +2 more sources

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

Advanced Science, EarlyView.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi, Zesheng Li, Xin Sun, Yanfeng Yang, Yumin Luo, Ziang Song, Hengxin Dong, Lei Jin, Jing Xie, Yongzhi Shan, Guoguang Zhao   +10 more
wiley   +1 more source

Soil microorganism colonization influenced the growth and secondary metabolite accumulation of Bletilla striata (Thunb.) Rchb. F. [PDF]

BMC Microbiol
Xu Q, Fu Y, Zhang J, Xu C, Yang C, Yuan Q, Xu J, Jiang W, Zhang Y, Zhou T, Xiao C.   +10 more
europepmc   +1 more source

Chemistry and biological activity of the secondary metabolites of vismieae

, 1985
Franco Delle Monachè
openalex   +1 more source

Optimizing Nitrogen Nutrient Management for the Sustainable Enhancement of Secondary Metabolites and Yield in Onion Cultivation [PDF]

Katarína Olšovská, Andrea Golisova, Oksana Sytar   +2 more
openalex   +1 more source