Results 21 to 30 of about 3,541,226 (351)

The secondary metabolite bioinformatics portal: Computational tools to facilitate synthetic biology of secondary metabolite production

Synthetic and Systems Biotechnology, 2016
Natural products are among the most important sources of lead molecules for drug discovery. With the development of affordable whole-genome sequencing technologies and other ‘omics tools, the field of natural products research is currently undergoing a ...
Tilmann Weber, Hyun Uk Kim
doaj   +1 more source

Antioxidant, Antibacterial and Antifungal Activities of Different Extracts of Silybum marianum Collected from Duhok (Iraq)

International Journal of Secondary Metabolite, 2020
In this study, antioxidant, antibacterial and antifungal activities of Silybum marianum (L.) Gaertn. collected from Duhok (Iraq) were determined. Ethanol, methanol and dichloromethane extracts of the fruit part of plant were obtained.
Falah Saleh Mohammed, Mustafa Pehlivan, Mustafa Sevindik   +2 more
doaj   +1 more source

MultiMetEval: comparative and multi-objective analysis of genome-scale metabolic models [PDF]

, 2012
Comparative metabolic modelling is emerging as a novel field, supported by the development of reliable and standardized approaches for constructing genome-scale metabolic models in high throughput.
A Freitag, A Gevorgyan, A Mithani, Albert Gevorgyan, AM Feist, AM Feist, AM Feist, Andrzej M. Kierzek, AP Burgard, BA Pfeifer, CS Henry, D Nagrath, DC Alexander, DC Stevens, EM Paradise, Eriko Takano, FC Lee, H Ikeda, I Thiele, J Gonzalez-Lergier, J Romero, J Schellenberger, JD Orth, JL Adrio, JP Brooks, JS Edwards, K Nieselt, K Yanai, LM Blank, M DeJongh, M Durot, M Kanehisa, M Latendresse, MA Fischbach, MA Oberhardt, MA Oberhardt, MA Oberhardt, Marnix H. Medema, MH Medema, MH Medema, MH Medema, MH Medema, MT Alam, MT Alam, MW Covert, N Scherr, ND Price, ND Price, NE Lewis, Piotr Zakrzewski, PR Ives, R Breitling, R Schuetz, Rainer Breitling, SA Becker, SD Bentley, Stephen S. Fong, TD Vo, TY Kim, XQ Zhao   +59 more
core   +6 more sources

Screening of secondary metabolite biosynthesis genes of marine actinomycetes isolated from Trabzon (Black Sea) sea sediments

Turkish Journal of Agriculture: Food Science and Technology, 2017
In this study, active secondary metabolite production capacity of actinomycete isolates obtained from Trabzon (Black Sea) sea sediments was investigated by molecular techniques.
Kadriye Özcan
doaj   +1 more source

Determination of the Health Services Vocational School Students’ Thoughts and Usage Habits about Herbal Treatment

International Journal of Secondary Metabolite, 2017
Usage of complementary-alternative medicine (CAM) is increasing in a rapid manner. Among CAM, herbal applications come in the foreground. This cross-sectional study was conducted by using ‘questionnaire application method’ on 342 students in Inonu ...
Gülsüm Yetiş, Turgay Kolaç, Perihan Gürbüz, Zehra Deniz Yakıncı   +3 more
doaj   +1 more source

Does Osmotic Stress Affect Natural Product Expression in Fungi? [PDF]

, 2017
Acknowledgments: Russell Kerr acknowledges the assistance of Nadia Prigoda-Lee, Marius Grote, Kate McQuillan and Stephanie Duffy, and generous financial support from NSERC, the Canada Research Chair program, the Jeanne and Jean-Louis Lévesque Foundation ...
Bills, Gerald, Capon, Rob, Chi, Wei Chiung, Correa, Hebelin, Ebel, Rainer, Kerr, Russell, Overy, David, Pang, Ka Lai, Rateb, Mostafa, Roullier, Catherine, Shang, Zhuo   +10 more
core   +3 more sources

The Effects of Domestication on Secondary Metabolite Composition in Legumes

Frontiers in Genetics, 2020
Legumes are rich in secondary metabolites, such as polyphenols, alkaloids, and saponins, which are important defense compounds to protect the plant against herbivores and pathogens, and act as signaling molecules between the plant and its biotic ...
Yee-Shan Ku, C. Contador, Ming-Sin Ng, Jeongjun Yu, G. Chung, H. Lam   +5 more
semanticscholar   +1 more source

Finding New Cell Wall Regulatory Genes in Populus trichocarpa Using Multiple Lines of Evidence. [PDF]

, 2019
Understanding the regulatory network controlling cell wall biosynthesis is of great interest in Populus trichocarpa, both because of its status as a model woody perennial and its importance for lignocellulosic products.
Chen, Jin-Gui, DiFazio, Stephen, Dixon, Richard A, Furches, Anna, Gazolla, Joao Gabriel Felipe Machado, Jacobson, Daniel, Jones, Piet, Joubert, Wayne, Kainer, David, Large, Annabel, Macaya-Sanz, David, Martin, Madhavi Z, Ranjan, Priya, Rao, Xiaolan, Romero, Jonathon, Schmutz, Jeremy, Shah, Manesh, Sreedasyam, Avinash, Streich, Jared, Tschaplinski, Timothy J, Tuskan, Gerald A, Walker, Angelica M, Weighill, Deborah, Zhao, Nan   +23 more
core   +3 more sources

A Penicillium rubens platform strain for secondary metabolite production

Scientific Reports, 2020
We present a Penicillium rubens strain with an industrial background in which the four highly expressed biosynthetic gene clusters (BGC) required to produce penicillin, roquefortine, chrysogine and fungisporin were removed.
Carsten Pohl, Fabiola Polli, Tabea Schütze, A. Viggiano, László Mózsik, Sascha Jung, M. D. De Vries, R. Bovenberg, V. Meyer, A. Driessen   +9 more
semanticscholar   +1 more source

Metabolic modeling and analysis of the metabolic switch in Streptomyces coelicolor [PDF]

, 2010
Background The transition from exponential to stationary phase in Streptomyces coelicolor is accompanied by a major metabolic switch and results in a strong activation of secondary metabolism.
Alam, Mohammad T., Breitling, Rainer, HASH(0x55aa09327868), Hodgson, D. A., Merlo, Maria E., Takano, Eriko, Wellington, E. M. H.   +6 more
core   +13 more sources