Results 31 to 40 of about 215,278 (261)

Essential Oil Composition of Endemic Sideritis leptoclada O. Schwarz& P. H. Davis (Lamiaceae) from Turkey by Using Two-Dimensional Gas Chromatography-Time-of-Flight Mass Spectrometry (GCxGC-TOF/MS)

International Journal of Secondary Metabolite, 2017
Sideritis genus is present by 46 species in Turkey with high endemism rate (ca. 82%). The chemical composition of essential oil obtained from the aerial parts of endemic Sideritis leptoclada O. Schwarz & P. H. Davis was investigated.
Gürkan SEMİZ, Mustafa Zafer ÖZEL
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Extraction of antioxidative principles of Achillea biserrata M. Bieb. and chromatographic analyses

International Journal of Secondary Metabolite, 2015
In this study, hexane, chloroform and water extracts were prepared by making consecutive extraction of Achillea biserrata from the family Asteraceae.
Gönül SERDAR, Münevver SÖKMEN, Ezgi DEMİR, Atalay SÖKMEN, Ersan BEKTAŞ   +4 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

A Comparative Study on Antioxidant and Antibacterial Activities of Four Senecio Species From Turkey

International Journal of Secondary Metabolite, 2015
The present study was conducted to investigate total phenolic content, antioxidant and antibacterial activity of four Senecio L. (Asteraceae). The in vitro antioxidant activities of extracts were evaluated with different antioxidant testing systems ...
Sevil ALBAYRAK, Ahmet AKSOY, Lutfiye YURTSEVEN, Abit YAŞAR   +3 more
doaj   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Protective Effects of Selenopyran Against Carbon Tetrachloride Hepatotoxicity in Rats

International Journal of Secondary Metabolite, 2014
Carbon tetrachloride (CCl4) is a known hepatotoxic compound working through the generation of reactive free radicals. Selenium (Se) is an essential trace element required by animals and humans for protection against xenobiotic compounds.
L. B. ZAVODNIK, D. B. VOLOSHIN, A. SKOMOROSHKO, T. N. BUDKO1, V. I. KONDAKOV, R. N. LIAKH1, A. M. KHOKHA, B. PALECZ   +7 more
doaj  

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

secondary metabolites [PDF]

, 2014
Citation: 'secondary metabolites' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.S05526 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley   +1 more source