Results 111 to 120 of about 7,098,586 (333)

Secondary plant metabolites as targets for genetic modification of crop plants for pest resistance.

, 1989
Three genetic manipulation strategies are described for enhancing the effectiveness of secondary metabolites of crop plants in reducing pest and disease damage. Targets for gene transfer studies are secondary metabolites of oilseed rape, lepidopteran sex
Pickett, J. A., Mudd, A., Dawson, G. W., Dawson, G., Wadhams, L., Wallsgrove, R. M., Wallsgrove, R., Hallahan, D., Hallahan, D. L., Patel, M. M., Pickett, J., Patel, M., Wadhams, L. A.   +12 more
core   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu   +10 more
wiley   +1 more source

Untargeted NMR-Based Methodology in the Study of Fruit Metabolites

Molecules, 2015
In this review, fundamental aspects of the untargeted NMR-based methodology applied to fruit characterization are described. The strategy to perform the structure elucidation of fruit metabolites is discussed with some examples of spectral assignments by
Anatoly Petrovich Sobolev, Luisa Mannina, Noemi Proietti, Simone Carradori, Maria Daglia, Anna Maria Giusti, Riccarda Antiochia, Donatella Capitani   +7 more
doaj   +1 more source

Secondary Metabolites Profiled in Cannabis Inflorescences, Leaves, Stem Barks, and Roots for Medicinal Purposes

Scientific Reports, 2020
Cannabis research has historically focused on the most prevalent cannabinoids. However, extracts with a broad spectrum of secondary metabolites may have increased efficacy and decreased adverse effects compared to cannabinoids in isolation.
Dan Jin, Kaiping Dai, Zhen Xie, Jie Chen
semanticscholar   +1 more source

An Engineered Biomimetic Nanoreactor With Cascade Functions for Targeted and Combinatorial Therapy of Ischemic Stroke

Advanced Healthcare Materials, EarlyView.
Preparation of RVG‐modified erythrocyte membrane‐coated HMPB nanocarriers loaded with L‐arginine and NBP (RM@HPAN) and its neuroprotective mechanism. After intravenous injection, RM@HPAN achieves prolonged circulation, RVG‐29‐mediated BBB penetration, and ischemic accumulation.
Shaofa Li, Ying Wu, Huimin Wei, Jinyong Teng, Zaizhi Yang, Jufang Chen, Bao Liao, Xiaoqin Huang, Lanqing Meng, Tong Li   +9 more
wiley   +1 more source

Polyphenol‐Inspired Materials for Agricultural Applications

Advanced Materials, EarlyView.
This review outlines the use of polyphenol‐inspired materials for sustainable agriculture, highlighting their molecular design, interfacial assembly, structure–property relationships, and prospects toward precision agriculture, climate resilience, ecosystem protection, and circular bioeconomy strategies.
Haofu Liu, Omid Mazaheri, Zhixing Lin, Tianzheng Wang, Jingqu Chen, Yuang Gu, Xia Liang, Deli Chen, Frank Caruso   +8 more
wiley   +1 more source

Smart Antibacterial Coatings: Harnessing Bacterial Redox Activity for Infection Control

Advanced Materials Interfaces, EarlyView.
In this study, we have shown that ceftazidime‐loaded poly(3,4‐ethylenedioxythiophene) (PEDOT@CAZ) functions as a smart, redox‐responsive antibacterial coating that couples bacterial electrical activity with localized antibiotic delivery. Shewanella oneidensis and Pseudomonas aeruginosa induced distinct redox responses in PEDOT, reflecting their ...
Abdullah, Szymon Smołka, Kamran Ayaz, Sara Shakibania, Sajida Maryam, Taral Patel, Roman Turczyn, Ewa Zabłocka‐Godlewska, Katarzyna Krukiewicz   +8 more
wiley   +1 more source

Chemodiversity of Annona Squamosa Secondary Metabolites [PDF]

SINAI International Scientific Journal
Annona squamosa a member of the Annonaceae family is an important fruit cultivated in Egypt, Bermuda, Brazil, India, Mexico, South and Central America, considered a notable source of secondary metabolites with a broad range of biological activities ...
Mohamed Abdel-Azeem, Enas E. Eltamany, Marwa S. Goda, Jihan M. Badr   +3 more
doaj   +1 more source

Characterisation of secondary metabolites associated with neutrophil apoptosis [PDF]

, 1996
We studied changes in secondary metabolites in human neutrophils undergoing constitutive or tumour necrosis factor (TNFα) stimulated apoptosis by a combination of high-performance liquid chromatography (HPLC) and NMR spectroscopy.
Maria L. Barnard, Chilvers, Edwin J., Nunn, A.V.W., Kishore Bhakoo, Bhakoo, Kishore, Bell, J.D., Nunn, Alistair V.W., Bell, Jimmy D., Barnard, Maria L., Joanna Murray, Edwin J. Chilvers, Barnard, M.L., Murray, J., Chilvers, E.J., Jimmy D. Bell, Murray, Joanna, Alistair V.W. Nunn, Bhakoo, K.K.   +17 more
core   +1 more source