Results 231 to 240 of about 3,896,821 (401)

Secondary Metabolites Produced by Macrophomina phaseolina Isolated from Eucalyptus globulus [PDF]

, 2020
Maria Michela Salvatore, Carina Félix, Fernanda Blauth de Lima, Vanessa Ferreira, Daniele Naviglio, Francesco Salvatore, Ana Sofia Duarte, Artur Alves, Anna Andolfi, Ana Cristina Esteves   +9 more
openalex   +1 more source

HRS Degradation‐Induced Nicotinamide Deficiency in Placental Extracellular Vesicles Triggers Preeclampsia by Disrupting Maternal‐Fetal Immune Homeostasis

Advanced Science, EarlyView.
This study shows that lower NAM levels in PE‐derived pEVs correlate with disease severity. NAM‐deficient pEVs reduce Th1 and Th17 inhibition, leading to PE‐like symptoms. NAM in pEVs inhibits Th1 via SIRT1 and Th17 via macrophages. Reduced NAM in PE‐EVs is due to decreased HRS expression in trophoblasts, resulting from elevated HSP27.
Haiyi Fei, Yuhan Lin, Xiu Liu, Xiaohong Zhu, Xiaowen Lu, Zhan Shi, Fan Jia, Shiqian Xu, Ling Fang, Lingling Jiang, Songying Zhang   +10 more
wiley   +1 more source

Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells

Advanced Science, EarlyView.
Alkyltriphenylphosphonium, exemplified by TPP+‐C14, preferentially accumulates in mitochondria and selectively binds to cardiolipin, a key phospholipid of the inner mitochondrial membrane, causing loss of mitochondrial membrane potential, severe cellular ATP depletion, and calcium imbalance.
Jin Li, Hang Zheng, Yuxing Lin, Ziwei Zhao, Yijia Mai, Zhangrong Lou, Qiang Liu, Zhao Ma, Chengjun Wu   +8 more
wiley   +1 more source

Anticancer Secondary Metabolites Produced by Fungi: Potential and Representative Compounds. [PDF]

Int J Mol Sci
García-Estrada C, Barreiro C, Martín JF.   +2 more
europepmc   +1 more source

Response of secondary metabolites in Aristolochia bracteolata Lam. under water stress regimes

, 2021
Madhuri P. Patil, Shashikant J. Chavan, Chandrashekhar Murumkar   +2 more
openalex   +1 more source

Urgency and Mechanism of Biosynthesis of Marine Microbial Secondary Metabolites

, 2020
Albetina Sedaca
openalex   +1 more source

A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells

Advanced Science, EarlyView.
An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet, Sara Pugliese, Jordi Bruna, Daniel Ruiz‐Molina, Salvio Suárez‐García, Victor J. Yuste   +5 more
wiley   +1 more source

Siderophores and secondary metabolites produced by <i>Ganoderma adspersum</i>. [PDF]

Microbiology (Reading)
Reyes C, Ahrendt S, Riley R, Lipzen A, Ng V, Grigoriev IV, Schwarze FWMR, Baars O.   +7 more
europepmc   +1 more source

G‐protein signalling mediates differential production of toxic secondary metabolites [PDF]

, 2000
Andrew G. Tag, Julie K. Hicks, Gulnara F. Garifullina, Charles Ake, T. D. Phillips, Marian N. Beremand, Nancy P. Keller   +6 more
openalex   +1 more source

ACSL5 Regulates Glucose Metabolism and Chemotherapy Sensitivity in Colorectal Cancer Cells under Glutamine Deficiency

Advanced Science, EarlyView.
Glutamine deprivation triggers ACSL5 upregulation in tumor cells, sustaining their viability via dual metabolic rewiring programs. ACSL5 enhances glycolysis by relieving p53's inhibition of PGAM1 while also sustaining mitochondrial respiration and TCA cycle flux through promoting IDH2 dimerization.
Shuai Tian, Qiaoxia Zhang, Xuedan Sun, Rick Francis Thorne, Zeyuan Shi, Qiang Ji, Zhangran Sun, Yuanxiang Lu, Qun Zhao, Xianjun Yu, Wanglai Hu, Mian Wu   +11 more
wiley   +1 more source