Results 261 to 270 of about 676,672 (336)

Phytosome-Enhanced Secondary Metabolites for Improved Anticancer Efficacy: Mechanisms and Bioavailability Review. [PDF]

Drug Des Devel Ther
Mardiana L, Milanda T, Hadisaputri YE, Chaerunisaa AY.   +3 more
europepmc   +1 more source

Longitudinal Metabolomics in Amyotrophic Lateral Sclerosis Implicates Impaired Lipid Metabolism

Annals of Neurology, EarlyView.
Objective Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by altered metabolome and energy homeostasis, manifesting with body mass index changes and hypermetabolism—both prognostic of disease progression and survival.
Kai Guo, Masha G. Savelieff, Dae‐Gyu Jang, Samuel J. Teener, Lili Zhao, Junguk Hur, Stephen A. Goutman, Eva L. Feldman   +7 more
wiley   +1 more source

Evaluating the Efficacy of Secondary Metabolites in Antibiotic-Induced Dysbiosis: A Narrative Review of Preclinical Studies. [PDF]

Antibiotics (Basel)
Andrei C, Zanfirescu A, Ormeneanu VP, Negreș S.   +3 more
europepmc   +1 more source

Crystallization of L‐Cysteine in Heavy Water Induces Intrinsic Fluorescence

Angewandte Chemie, EarlyView.
Crystallization of L‐Cysteine in D2O${\rm D}_2{\rm O}$ generates a remarkably different structure compared to H2O${\rm H}_2{\rm O}$. The crystals formed in D2O${\rm D}_2{\rm O}$ display enhanced intrinsic fluorescence, and using state‐of‐the‐art excited state simulations, we determine the molecular origins of this luminescence and propose design ...
Debarshi Banerjee, Sonika Chibh, Om Shanker Tiwari, Gonzalo Díaz Mirón, Marta Monti, Hadar R. Yakir, Shweta Pawar, Dror Fixler, Linda J. W. Shimon, Ehud Gazit, Ali Hassanali   +10 more
wiley   +2 more sources

New Horizons for Multiple Sclerosis Therapy: 2025 and Beyond

Annals of Neurology, EarlyView.
The advances achieved against multiple sclerosis (MS) represent one of the great success stories of modern molecular medicine. The development of therapies with increasing selectivity and safety, guided by gains in understanding the fundamental immunology, neurobiology, genetics, and triggers of this disease, have broadened the traditional focus on ...
Joseph J. Sabatino Jr., Bruce A. C. Cree, Stephen L. Hauser   +2 more
wiley   +1 more source

Secondary Metabolites from <i>Bacillus</i> spp. probiotics as potential treatments for multidrug-resistant pathogens: A comprehensive review. [PDF]

Curr Res Microb Sci
Nicolas GM.
europepmc   +1 more source

Autosomal Recessive Cerebellar Ataxias: Translating Genes to Therapies

Annals of Neurology, EarlyView.
Autosomal recessive cerebellar ataxias are disabling neurodegenerative genetic conditions affecting balance and coordination. Advancements in genomic testing have improved diagnosis, leading to a new focus on the development of targeted precision therapeutics addressing cellular, biochemical, and genetic disease mechanisms with a resulting emphasis on ...
Brent L. Fogel, Thomas Klopstock, David R. Lynch, Francesca Maltecca, Mayank Verma, Berge A. Minassian, Frances M. Platt, Débora Farina Gonçalves, Hélène Puccio, Andreas Roos, Matthis Synofzik   +10 more
wiley   +1 more source

Unraveling the response of secondary metabolites to cold tolerance in oil palm by integration of physiology and metabolomic analyses. [PDF]

BMC Plant Biol
Song Y, John Martin JJ, Liu X, Li X, Hou M, Zhang R, Xu W, Li W, Cao H.   +8 more
europepmc   +1 more source

A comprehensive review of factors affecting growth and secondary metabolites in hydroponically grown medicinal plants. [PDF]

Planta
Venkatasai NN, Shetty DN, Vinay CM, Sekar M, Muthusamy A, Rai PS.   +5 more
europepmc   +1 more source

Dynamic Variation of Secondary Metabolites from <i>Polygonatum cyrtonema</i> Hua Rhizomes During Repeated Steaming-Drying Processes. [PDF]

Molecules
Wang S, He F, Hu R, Wan X, Wu W, Zhang L, Ho CT, Li S.   +7 more
europepmc   +1 more source