Results 81 to 90 of about 7,098,586 (333)
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Plants Secondary Metabolites as Blood Glucose-Lowering Molecules
Molecules, 2021 Recently, significant advances in modern medicine and therapeutic agents have been achieved. However, the search for effective antidiabetic drugs is continuous and challenging.
Mayadah B. Shehadeh +2 more
semanticscholar +1 more source
Plant Secondary Metabolites: Occurrence, Structure and Role in the Human Diet
, 2020 Plant secondary metabolites have been a fertile area of chemical investigation for many years, driving the development of both analytical chemistry and of new synthetic reactions and methodologies.
Ashihara, H, Crozier, A, Clifford, MN
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Two New Secondary Metabolites from
Natural Product Communications, 2015 Further investigation of Tephrosia purpurea led to the isolation of a new prenylated flavone, isoglabratephrin B (1) and a new 1,2-ethanedione benzofuran derivative, purpdione B (2) .
Yin-Ning Chen +8 more
doaj +1 more source
Stress and defense responses in plant secondary metabolites production
Biological Research, 2019 In the growth condition(s) of plants, numerous secondary metabolites (SMs) are produced by them to serve variety of cellular functions essential for physiological processes, and recent increasing evidences have implicated stress and defense response ...
T. Isah
semanticscholar +1 more source
International Journal of Molecular Sciences, 2021 Secondary metabolites isolated from plant endophytic fungi have been getting more and more attention. Some secondary metabolites exhibit high biological activities, hence, they have potential to be used for promising lead compounds in drug discovery.
Ruihong Zheng +3 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
wiley +1 more source
Secondary Metabolites from the Liverwort
Natural Product Communications, 2009 A new trinortriterpenoid, diospyrolide acetate (1) and a new diphenylmethane derivative, pulcherrimumin (12), together with ten known pentacyclic triterpenoids (2–11) and four aromatic compounds (13–16), were isolated from the liverwort Ptilidium ...
Dong-Xiao Guo +6 more
doaj +1 more source
Applications of CRISPR/Cas9 in the Synthesis of Secondary Metabolites in Filamentous Fungi
Frontiers in Microbiology, 2021 Filamentous fungi possess the capacity to produce a wide array of secondary metabolites with diverse biological activities and structures, such as lovastatin and swainsonine.
Chun-Miao Jiang +6 more
semanticscholar +1 more source