Results 81 to 90 of about 4,217,021 (297)
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Reaction-controlled phase transferred catalysis for selective oxidation of alcohols
A reaction-controlled phase transfer catalyst for oxidation of secondary alcohols with high selectivity was ...
Xi, ZW +4 more
core
Oxidation kinetics of a Ni-Cu based cermet at high temperature [PDF]
The oxidation kinetics of a cermet composed of Ni–Cu alloy and nickel ferrite was studied by thermogravimetry at 960 °C under oxygen in the range 0.5–77 kPa. After an initial mass increase up to 15 g/m2 due to oxidation of surface metallic particles, the
Palau, Patrice +14 more
core +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Oxidation products of sulfamethoxazole in ozonated secondary effluent
In this study the antibiotic sulfamethoxazole (SMX) was subjected to ozone treatment. Solutions of 60 mg/L and 100 microg/L SMX in pure water and secondary municipal effluent were treated. The removal profile of SMX and its oxidation products was monitored as a function of transferred ozone dose in both matrices. No difference was observed in the ozone
Rodayan, Angela +2 more
openaire +3 more sources
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis +20 more
wiley +1 more source
This study investigates the effect of different packaging methods—namely, air packaging (AP), vacuum packaging (VP), and modified atmosphere packaging (MAP)—on the protein oxidation and degradation of grouper (Epinephelus coioides) fillets ...
Xicai Zhang, Wenbo Huang, Jing Xie
doaj +1 more source
Enantioselective Oxidation of Secondary Alcohols Using a Chiral Nitroxyl (N-Oxoammonium salt ...
Hemaka Rajapakse (3036948) +2 more
core +1 more source
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source

