Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
School choice and implications for equity: the new political geography of the Swedish upper secondary school market [PDF]
, 2018 Anna-Maria Fjellman +2 more
openalex +1 more source
Student-Centered Learning Opportunities For Adolescent English Learners In Flipped Classrooms [PDF]
, 2016 This study documents opportunities for diverse adolescent English learners to deeply engage with content and language in flipped learning environments.
Avary Carhill-Poza, Panayota Gounari
core
FEBS Open Bio, EarlyView.Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source
Leading schools in the digital age: A clash of cultures [PDF]
, 2008 A cultural gap is widening in English secondary schools: between a twentieth-century ethos of institutional provision and the twenty-first century expectations and digital lifestyles of school students. Perhaps disaffected by traditional teaching methods
Williams, Peter
core +1 more source
Naked cuticle is essential for Drosophila wing development beyond Wingless signaling
FEBS Open Bio, EarlyView.Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley +1 more source
Dietary Patterns and Cardiovascular Risk Factors in Spanish Adolescents: A Cross-Sectional Analysis of the SI! Program for Health Promotion in Secondary Schools [PDF]
, 2019 Patricia Bodega +15 more
openalex +1 more source
FEBS Open Bio, EarlyView.What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman +4 more
wiley +1 more source
To the tolerance and peaceful coexistence through the Holy Books
Studia Humanitatis, 2014 The article is devoted to the questions of tolerance in the sphere of religious interconfessional relations. The authors analyze the texts of the Bible and the Quran – and draw the conclusions of possibility in keeping and multiplying religious dialogue ...
Melkova Elena Petrovna +1 more
doaj
A longitudinal study of upper secondary school students’ values and beliefs regarding policy responses to climate change [PDF]
, 2018 Caroline Ignell +2 more
openalex +1 more source