Results 71 to 80 of about 12,303,796 (305)
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
School engagement, self-esteem and wellbeing during transfer from primary to secondary school [PDF]
, 2009 For many years, educators, psychologists and parents have expressed concern about the apparent deterioration of pupil motivation and performance after children move to secondary school.
Horobin, M. Vivienne
core +2 more sources
The Scientific World Journal, 2015 This research studies the characterization of activated carbon from tamarind seed with KOH activation. The effects of 0.5 : 1–1.5 : 1 KOH : tamarind seed charcoal ratios and 500–700°C activation temperatures were studied. FTIR, SEM-EDS, XRD, and BET were
Sumrit Mopoung +3 more
doaj +1 more source
USE OF FILMS, PLATFORMS, AND EDUCATIONAL APPLICATIONS IN PRIMARY EDUCATION [PDF]
Romanian Review of Geographical EducationThe purpose of this study is to investigate primary school teachers' perceptions regarding the frequency of using educational platforms, digital applications, and videos for teaching science and geography.
Sanda VEREȘ +2 more
doaj +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
MONEY OR DIGITAL MONEY: TO BE OR NOT TO BE? [PDF]
Challenges of the Knowledge SocietyThe emergence of digital currencies has sparked debates about the future of money, raising questions about the viability of traditional currencies in an increasingly digital world.
Valentin Gabriel CRISTEA
doaj
WEBINAR IN SUPPORT OF STEAM TRAINING IN CLASS
Педагогически форум, 2019 A two-subjects webinar: information technology and arts with the participation of a lecturer from the Institute of Mathematics and Informatics and the Laboratory of Telematics of the Bulgarian Academy of Sciences is presented.
Toni Chehlarova +3 more
doaj +1 more source
Journal of Educational Sociology, 1940 "Selected references" at end of each chapter except the first. ; Mode of access: Internet.
openaire +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Formation of pupils’ key competences in Physics classes basing on the task-oriented approach
Науковий Вісник Південноукраїнського Національного Педагогічного Університету імені К. Д. Ушинського, 2019 The purpose of the study was the development, selection and implementation of high-quality physical tasks and situational tasks into the school course «Physics 8», as the conditions for positive motivation to study Physics and form pupils’ key ...
Kaplun Viktoriia +2 more
doaj +1 more source