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RNA Secondary Structures

2015
A topological RNA structure is derived from a diagram, and its shape is obtained by collapsing the stacks of the structure into single arcs and by removing any arcs of length one. Shapes contain key topological information, and for a fixed topological genus there exist only finitely many such shapes.
Qijun He, Matthew Macauley, Robin Davies
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Targeting DNA Secondary Structures

Current Medicinal Chemistry, 2000
DNA secondary structures containing regions of single-stranded DNA have now been identified in the genomic DNA of a number of prokaryotic and eukaryotic species, including humans. Many of these secondary structures are associated with regions of DNA involved in regulation of transcription: promoters or upstream elements.
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Protein Secondary Structure Prediction

2009
While the prediction of a native protein structure from sequence continues to remain a challenging problem, over the past decades computational methods have become quite successful in exploiting the mechanisms behind secondary structure formation. The great effort expended in this area has resulted in the development of a vast number of secondary ...
Pirovano, W.A., Heringa, J.
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RNA Secondary Structure Thermodynamics

2012
Several different ways to predict RNA secondary structures have been suggested in the literature. Statistical methods, such as those that utilize stochastic context-free grammars (SCFGs), or approaches based on machine learning aim to predict the best representative structure for the underlying ensemble of possible conformations.
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RNA Secondary Structures

2006
The three-dimensional structures of nucleic acids, RNA, and DNA, are dominated by double-helical regions that are formed by canonical Watson–Crick and wobble (GU) base pairs, which collectively are referred to as the secondary structure of the molecule.
Ivo L. Hofacker   +2 more
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Protein Secondary Structure

2010
There are several methods available that can be used to gain information on secondary structure, apart from X-ray crystallography, which remains the ‘gold standard’.
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Secondary Structure Prediction

2003
The aim of secondary structure prediction is to locate all α-helices and β- strands within a protein. We view the problem of secondary structure prediction as a statistical pattern recognition problem. We particularly focus on the sta- tistical analysis of the problem data.
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