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On the secondary structure in mRNA
Biosystems, 1977Abstract The sequence present in DNA phase transcripts have been investigated by Niyogi (1973) using a technique in which mRNA is enzymatically digested to yield different size classes that are resolved chromatographically into populations of equal chain lengths.
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Angewandte Chemie, 2018
Secondary structures such as α-helix and β-sheet are the major structural motifs within the three-dimensional geometry of proteins. Therefore, structure transitions from β-sheet to α-helix not only can serve as an effective strategy for the therapy of ...
Ruirui Xing +5 more
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Secondary structures such as α-helix and β-sheet are the major structural motifs within the three-dimensional geometry of proteins. Therefore, structure transitions from β-sheet to α-helix not only can serve as an effective strategy for the therapy of ...
Ruirui Xing +5 more
semanticscholar +1 more source
Analytical Biochemistry, 2000
We have expanded the reference set of proteins used in SELCON3 by including 11 additional proteins (selected from the reference sets of Yang and co-workers and Keiderling and co-workers).
N. Sreerama, R. Woody
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We have expanded the reference set of proteins used in SELCON3 by including 11 additional proteins (selected from the reference sets of Yang and co-workers and Keiderling and co-workers).
N. Sreerama, R. Woody
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Metrics on RNA Secondary Structures
Journal of Computational Biology, 2000Many different programs have been developed for the prediction of the secondary structure of an RNA sequence. Some of these programs generate an ensemble of structures, all of which have free energy close to that of the optimal structure, making it important to be able to quantify how similar these different structures are.
Moulton, Vincent +4 more
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Protein secondary structure prediction
Current Opinion in Structural Biology, 1995The past year has seen a consolidation of protein secondary structure prediction methods. The advantages of prediction from an aligned family of proteins have been highlighted by several accurate predictions made 'blind', before any X-ray or NMR structure was known for the family.
Jiri Novotny +2 more
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Genome-Wide Analysis of RNA Secondary Structure.
Annual Review of Genetics, 2016Single-stranded RNA molecules fold into extraordinarily complicated secondary and tertiary structures as a result of intramolecular base pairing. In vivo, these RNA structures are not static.
P. Bevilacqua +3 more
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2010
In principle we could expect that X-ray diffraction provides a complete picture of any protein that can be crystallized, with the exact position of each atom. Indeed, models displayed in showcases give the impression that the protein structure is fully known and has been found ab initio.
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In principle we could expect that X-ray diffraction provides a complete picture of any protein that can be crystallized, with the exact position of each atom. Indeed, models displayed in showcases give the impression that the protein structure is fully known and has been found ab initio.
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Statistics of RNA secondary structures
Biopolymers, 1993AbstractA statistical reference for RNA secondary structures with minimum free energies is computed by folding large ensembles of random RNA sequences. Four nucleotide alphabets are used: two binary alphabets, AU and GC, the biophysical AUGC and the synthetic GCXK alphabet. RNA secondary structures are made of structural elements, such as stacks, loops,
Peter F. Stadler +5 more
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Biopolymers, 2008
Circular dichroism (CD) spectroscopy has been a valuable method for the analysis of protein secondary structures for many years. With the advent of synchrotron radiation circular dichroism (SRCD) and improvements in instrumentation for conventional CD ...
L. Whitmore, B. Wallace
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Circular dichroism (CD) spectroscopy has been a valuable method for the analysis of protein secondary structures for many years. With the advent of synchrotron radiation circular dichroism (SRCD) and improvements in instrumentation for conventional CD ...
L. Whitmore, B. Wallace
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Nature, 1975
NUMEROUS attempts have been made to deduce a secondary structure of 5S RNA1–4. Differing approaches have yielded various structures, but each turns out to be inconsistent with either physical, chemical, biochemical, or comparative evidence. Clearly the situation is not analogous to that which obtained for transfer RNA (tRNA).
George E. Fox, Carl R. Woese
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NUMEROUS attempts have been made to deduce a secondary structure of 5S RNA1–4. Differing approaches have yielded various structures, but each turns out to be inconsistent with either physical, chemical, biochemical, or comparative evidence. Clearly the situation is not analogous to that which obtained for transfer RNA (tRNA).
George E. Fox, Carl R. Woese
openaire +3 more sources