Results 71 to 80 of about 19,445,077 (386)

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

A stochastic design rainfall generator based on copulas and mass curves [PDF]

, 2010
The use of design storms can be very useful in many hydrological and hydraulic practices. In this study, the concept of a copula-based secondary return period in combination with the concept of mass curves is used to generate point-scale design storms ...
Buyse, E, De Baets, Bernard, Vandenberghe, Sander, Verhoest, Niko   +3 more
core   +3 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Structural Analysis and Sensitization Prediction of the Allergic Proteins Ana o 2 and Ana o 3 in Cashew Nuts

Shipin gongye ke-ji, 2022
In order to definite the molecular structure and allergic characteristics of cashew nuts, the main allergic proteins were isolated and purified by organic solvent defatting, salting out, dialysis and Sephadex G-150 gel.
Ailin ZHANG, Huijuan ZHAO, Yue CHI, Xiaoyan LIANG, Xiaodan LI, Mei GUO   +5 more
doaj   +1 more source

Ground state and glass transition of the RNA secondary structure

, 2006
RNA molecules form a sequence-specific self-pairing pattern at low temperatures. We analyze this problem using a random pairing energy model as well as a random sequence model that includes a base stacking energy in favor of helix propagation.
Bundschuh, Bundschuh, Carpentier, Dill, Gennes, Halpin-Healy, Hartmann, Higgs, Hwa, Hwa, Isaacs, Jr, Jr, Karlin, Krzakala, L.-H. Tang, Lässig, Marinari, Mukhopadhyay, Mézard, Nussinov, Onuchic, Pagnani, S. Hui, Schueler-Furman, Shakhnovich, Snow, Tang, Tang, Yu, Zeng, Zuker   +31 more
core   +1 more source

The Carboxyl-Terminal Segment of Apolipoprotein A-V Undergoes a Lipid-Induced Conformational Change [PDF]

, 2010
Apolipoprotein (apo) A-V is a 343-residue, multidomain protein that plays an important role in regulation of plasma triglyceride homeostasis. Primary sequence analysis revealed a unique tetraproline sequence (Pro293-Pro296) near the carboxyl terminus of ...
Lee, B. L., Mauldin, Kasuen, Oleszczuk, M., Ryan, R. O., Sykes, B. D.   +4 more
core   +2 more sources

bpRNA: large-scale automated annotation and analysis of RNA secondary structure

bioRxiv, 2018
While RNA secondary structure prediction from sequence data has made remarkable progress, there is a need for improved strategies for annotating the features of RNA secondary structures.
Padideh Danaee, Mason N. Rouches, M. Wiley, Dezhong Deng, Liang Huang, D. Hendrix   +5 more
semanticscholar   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Streamwise vortex structure in plane mixing layers [PDF]

, 1986
The development of three-dimensional motions in a plane mixing layer was investigated experimentally. It is shown that superimposed on the primary, spanwise vortex structure there is a secondary, steamwise vortex structure.
Bernal, L. P., Roshko, A.
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source