Results 11 to 20 of about 537,132 (265)
mBio, 2020 The type VI secretion system (T6SS) is a critical weapon in bacterial warfare between Gram-negative bacteria. Although invaluable for niche establishment, this machine represents an energetic burden to its host bacterium.
Juvenal Lopez +2 more
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Bacterial Secretion Systems: An Overview [PDF]
Microbiology Spectrum, 2016 ABSTRACT Bacterial pathogens utilize a multitude of methods to invade mammalian hosts, damage tissue sites, and thwart the immune system from responding. One essential component of these strategies for many bacterial pathogens is the secretion of proteins across phospholipid membranes.
Erin R, Green, Joan, Mecsas
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Extra! Extracellular Effector Delivery into Host Cells via the Type 3 Secretion System
mBio, 2017 The type three secretion system (T3SS) is critical for the virulence of diverse bacterial pathogens. Pathogens use the T3SS to deliver effector proteins into host cells and manipulate host signaling pathways.
Melissa M. Kendall
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Microorganisms, 2020 Piscirickettsia salmonis is the causative bacterial agent of piscirickettsiosis, a systemic fish disease that significantly impacts the Chilean salmon industry.
Cristian Oliver +8 more
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Type III secretion system [PDF]
Current Biology, 2014 The type III secretion system (T3SS) is a membrane-embedded nanomachine found in several Gram-negative bacteria. Upon contact between bacteria and host cells, the syringe-like T3SS (Figure 1) transfers proteins termed effectors from the bacterial cytosol to the cytoplasm or the plasma membrane of a single target cell.
Puhar, Andrea, Sansonetti, Philippe J.
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Diversity, 2019 In recent years, the use of whole-cell biocatalysts and biocatalytic enzymes in biotechnological applications originating from the genus Pseudomonas has greatly increased.
Dominik Rutz +6 more
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eLife, 2023 CD8+ T cell recognition of Mycobacterium tuberculosis (Mtb)-specific peptides presented on major histocompatibility complex class I (MHC-I) contributes to immunity to tuberculosis (TB), but the principles that govern presentation of Mtb antigens on MHC-I
Owen Leddy +2 more
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mBio, 2017 Biofilms of sulfate-reducing bacteria (SRB) are of particular interest as members of this group are culprits in corrosion of industrial metal and concrete pipelines as well as being key players in subsurface metal cycling.
Kara B. De León +8 more
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Peptidomimetics as Potential Anti-Virulence Drugs Against Resistant Bacterial Pathogens
Frontiers in Microbiology, 2022 The uncontrollable spread of superbugs calls for new approaches in dealing with microbial-antibiotic resistance. Accordingly, the anti-virulence approach has arisen as an attractive unconventional strategy to face multidrug-resistant pathogens.
Osmel Fleitas Martínez +4 more
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mBio, 2017 The type 3 secretion system (T3SS) is essential for bacterial virulence through delivering effector proteins directly into the host cytosol. Here, we identified an alternative delivery mechanism of virulence factors mediated by the T3SS, which consists ...
Farid Tejeda-Dominguez +3 more
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