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Hypoxia and the Tumor Secretome
2019Metastasis remains the leading cause of cancer-related deaths. To date, there are no specific treatments targeting disseminated disease. New therapeutic options will become available only if we enhance our understanding of mechanisms underlying metastatic spread.
Ying, Liu +2 more
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2016
Through rapid advancement of genomics by Next Generation Sequencing (NGS) and proteomics by Mass Spectrometry (MS) technologies and innovative sampling and bioinformatic strategies a new era of personalized medicine is upon us. Secreted proteins play an important role in tumorigenesis through cell growth, migration, invasion, and angiogenesis. As such,
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Through rapid advancement of genomics by Next Generation Sequencing (NGS) and proteomics by Mass Spectrometry (MS) technologies and innovative sampling and bioinformatic strategies a new era of personalized medicine is upon us. Secreted proteins play an important role in tumorigenesis through cell growth, migration, invasion, and angiogenesis. As such,
openaire +1 more source
[Secretome: definitions and biomedical interest].
La Revue de medecine interne, 2008The secretome, or secretomics refers to the global study of proteins that are secreted by a cell, a tissue or an organism.The secretome is an important class of proteins that control many biological and physiological processes. Many secretion pathways are implicated in the release of these proteins.The secretome is a potential source suitable for the ...
Chenau, Jérôme +2 more
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Plant Secretomics: Unique Initiatives
2015Plant secretomics is an emerging subfield of proteomics studying proteins globally secreted into the extracellular space (apoplast) by plant cells at defined time under constitutive or induced conditions. Plant secretome has important biological functions in cell wall structure formation, cell-to-cell interaction, extracellular/intracellular signal ...
Neelam Yadav +2 more
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