Results 1 to 10 of about 242,930 (301)

Genome-scale modeling of the protein secretory machinery in yeast. [PDF]

PLoS ONE, 2013
The protein secretory machinery in Eukarya is involved in post-translational modification (PTMs) and sorting of the secretory and many transmembrane proteins.
Amir Feizi, Tobias Österlund, Dina Petranovic, Sergio Bordel, Jens Nielsen   +4 more
doaj   +17 more sources

The structure and dynamics of secretory component and its interactions with polymeric immunoglobulins [PDF]

eLife, 2016
As a first-line vertebrate immune defense, the polymeric immunoglobulin receptor (pIgR) transports polymeric IgA and IgM across epithelia to mucosal secretions, where the cleaved ectodomain (secretory component; SC) becomes a component of secretory ...
Beth M Stadtmueller, Kathryn E Huey-Tubman, Carlos J López, Zhongyu Yang, Wayne L Hubbell, Pamela J Bjorkman   +5 more
doaj   +2 more sources

Intramuscular mRNA BNT162b2 vaccine against SARS-CoV-2 induces neutralizing salivary IgA

Frontiers in Immunology, 2023
Intramuscularly administered vaccines stimulate robust serum neutralizing antibodies, yet they are often less competent in eliciting sustainable “sterilizing immunity” at the mucosal level.
Miri Stolovich-Rain, Miri Stolovich-Rain, Miri Stolovich-Rain, Sujata Kumari, Sujata Kumari, Sujata Kumari, Ahuva Friedman, Ahuva Friedman, Saveliy Kirillov, Saveliy Kirillov, Saveliy Kirillov, Saveliy Kirillov, Yakov Socol, Maria Billan, Maria Billan, Ritesh Ranjan Pal, Kathakali Das, Kathakali Das, Peretz Golding, Peretz Golding, Esther Oiknine-Djian, Salim Sirhan, Salim Sirhan, Michal Bejerano Sagie, Einav Cohen-Kfir, Naama Gold, Jamal Fahoum, Manoj Kumar, Maya Elgrably-Weiss, Bing Zhou, Miriam Ravins, Yair E. Gatt, Saurabh Bhattacharya, Orly Zelig, Reuven Wiener, Dana G. Wolf, Dana G. Wolf, Hila Elinav, Jacob Strahilevitz, Dan Padawer, Dan Padawer, Dan Padawer, Dan Padawer, Leah Baraz, Leah Baraz, Leah Baraz, Alexander Rouvinski, Alexander Rouvinski   +47 more
doaj   +1 more source

Equine Secretory IgA and Secretory Component [PDF]

International Archives of Allergy and Immunology, 1972
A complete secretory immunologic system has been identified in the equine species. It is characterised by the presence of a secretory component either bound to secretory IgA (SIgA) or remaining in the free form (FSC). The mean molecular weights of SIgA, serum IgA and FSC have been estimated.
Pahud, J.J., Mach, J.P.
openaire   +2 more sources

Histoarchitecture of Harderian Gland in Turkeys at Pre-pubertal Age

International Journal of Bio-Resource and Stress Management, 2023
The study was conducted during August, 2021 to June, 2022 at the Department of Veterinary Anatomy, Veterinary College and Research Institute, Namakkal, Tamilnadu, India to elucidate the histological features to provide reference to physiology ...
S. Jayachitra, S. Sivagnanam
doaj   +1 more source

Human Secretory Component

Scandinavian Journal of Immunology, 1974
A new purification method is based on a combination of conventional fractionation procedures (ammonium sulphate precipitation, gel filtration, and anionic‐exchange chromatography) and immunological removal of contaminating proteins. The immunosorbent was prepared by polymerizing antisera to human serum and colostrum and was used in a batch procedure ...
Charlotte Cunningham-Rundles, Michael E. Lamm, Edward C. Franklin   +2 more
  +6 more sources

Sprouty2 limits intestinal tuft and goblet cell numbers through GSK3β-mediated restriction of epithelial IL-33

Nature Communications, 2021
Dynamic regulation of colonic secretory cell numbers is a critical component of the response to intestinal injury and inflammation. Here, the authors show that loss of the intracellular signalling regulator Sprouty2 in the intestinal epithelial cells is ...
Michael A. Schumacher, Jonathan J. Hsieh, Cambrian Y. Liu, Keren L. Appel, Amanda Waddell, Dana Almohazey, Kay Katada, Jessica K. Bernard, Edie B. Bucar, Safina Gadeock, Kathryn M. Maselli, M. Kay Washington, Tracy C. Grikscheit, David Warburton, Michael J. Rosen, Mark R. Frey   +15 more
doaj   +1 more source

Extracellular Nicotinamide Phosphoribosyltransferase Is a Component of the Senescence-Associated Secretory Phenotype

Frontiers in Endocrinology, 2022
Cellular senescence is a stress or damage response by which a cell adopts of state of essentially permanent proliferative arrest, coupled to the secretion of a number of biologically active molecules. This senescence-associated secretory phenotype (SASP)
Chisaka Kuehnemann, Chisaka Kuehnemann, Kang-Quan Hu, Kayla Butera, Sandip K. Patel, Joanna Bons, Birgit Schilling, Cristina Aguayo-Mazzucato, Christopher D. Wiley   +8 more
doaj   +1 more source

A novel two-component system involved in secretion stress response in Streptomyces lividans. [PDF]

PLoS ONE, 2012
BACKGROUND: Misfolded proteins accumulating outside the bacterial cytoplasmic membrane can interfere with the secretory machinery, hence the existence of quality factors to eliminate these misfolded proteins is of capital importance in bacteria that are ...
Sonia Gullón, Rebeca L Vicente, Rafael P Mellado   +2 more
doaj   +1 more source

Combining manipulation of integration loci and secretory pathway on expression of an Aspergillus niger glucose oxidase gene in Trichoderma reesei

Microbial Cell Factories, 2023
Trichoderma reesei (T. reesei) is well-known for its excellent ability to secret a large quantity of cellulase. However, unlike the endogenous proteins, little is known about the molecular mechanisms governing heterologous protein production.
Wangli Ji, Xiaolu Wang, Xiaoqing Liu, Yuan Wang, Fangui Liu, Bo Xu, Huiying Luo, Tao Tu, Wei Zhang, Xinxin Xu, Xiaoyun Su   +10 more
doaj   +1 more source