Lactadherin inhibits secretory phospholipase A2 activity on pre-apoptotic leukemia cells. [PDF]
PLoS ONE, 2013 Secretory phospholipase A2 (sPLA2) is a critical component of insect and snake venoms and is secreted by mammalian leukocytes during inflammation. Elevated secretory PLA2 concentrations are associated with autoimmune diseases and septic shock. Many sPLA2'
Steffen Nyegaard +3 more
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Chloride channels regulate differentiation and barrier functions of the mammalian airway. [PDF]
, 2020 The conducting airway forms a protective mucosal barrier and is the primary target of airway disorders. The molecular events required for the formation and function of the airway mucosal barrier, as well as the mechanisms by which barrier dysfunction ...
Caplan, Michael J +14 more
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Drosophila KDEL receptor function in the embryonic salivary gland and epidermis. [PDF]
PLoS ONE, 2013 Core components of the secretory pathway have largely been identified and studied in single cell systems such as the budding yeast S. cerevisiae or in mammalian tissue culture.
Elliott W Abrams +2 more
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Secretory-component-producing lung cancer with hypergammaglobulinemia of secretory igA [PDF]
Cancer, 1981 Studies were made on a case of well-differentiated adenocarcinoma of the lung in which the serum levels of secretory IgA (sIgA) were very high. Immunofluorescent studies showed that secretory component (SC) was found to be diffusely distributed in cancer cells.
T, Gotoh +3 more
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Advanced Science, 2023 Tissue‐infiltrating neutrophils (TINs) secrete various signaling molecules to establish paracrine communication within the inflammatory milieu. It is imperative to identify molecular mediators that control this secretory phenotype of TINs.
Jia Song +17 more
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ATP: The crucial component of secretory vesicles [PDF]
Proceedings of the National Academy of Sciences, 2016 Significance ATP is highly concentrated in secretory vesicles. In vitro experiments suggest that the association of ATP with catecholamines reduces their osmotic forces, permitting the extraordinary accumulation of amines within chromaffin granules. However, this has yet to be proved in living cells. Because functional cells cannot be
Estévez Herrera, Judith +6 more
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Regulation of gastric acid secretion in situ by an endogenous activator protein: Studies with activator-specific antibody [PDF]
, 2013 Monospecific polyclonal antibody was raised against a homogenous preparation of endogenous activator protein (HAF) for the gastric H+,K+-ATPase system.
Tushar K. Ray, Jyotirmoy Nandi, Larry F. Lemanski and Swapan K. Ghosh
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The Aspergillus nidulans peripheral ER: disorganization by ER stress and persistence during mitosis. [PDF]
PLoS ONE, 2013 The genetically amenable fungus Aspergillus nidulans is well suited for cell biology studies involving the secretory pathway and its relationship with hyphal tip growth by apical extension.
Ane Markina-Iñarrairaegui +3 more
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TNF-α mediated secretory component is positively regulated by PI3K/AKT/mTOR in Caco-2 cells [PDF]
Journal of Medical Biochemistry, 2013 Background: Secretory component (SC) is the extracellular component of the polymeric immunoglobulin receptor (pIgR) that functions as a receptor for externally secreted polymeric immunoglobulins such as secretory IgA.
Liu Dongyan +3 more
doaj
Endoplasmic Reticulum Export of GPI-Anchored Proteins [PDF]
, 2019 Protein export from the endoplasmic reticulum (ER) is an essential process in all eukaryotes driven by the cytosolic coat complex COPII, which forms vesicles at ER exit sites for transport of correctly assembled secretory cargo to the Golgi apparatus ...
López Martín, Sergio +3 more
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