Results 261 to 270 of about 242,930 (301)

Effect of nicotine on secretory component synthesis by secretory epithelial cells

Clinical Diagnostic Laboratory Immunology, 1996
Previously, we reported that secretory component (SC), lactoferrin (LF), and lysozyme (LY) levels were significantly lower in saliva from smokeless tobacco (ST) users than in saliva from control non-tobacco users. However, the levels of salivary immunoglobulin A were significantly higher, albeit with an altered attachment of SC, in ST users than in ...
R L, Gregory, L E, Gfell
openaire   +2 more sources

Secretory component in pulmonary adenocarcinoma and mesothelioma

Histopathology, 1986
The distribution of secretory component was examined by an immunoperoxidase method in 40 pulmonary adenocarcinomas, 11 malignant pleural mesotheliomas and areas of normal lung adjacent to the tumours. Secretory component was demonstrated in tumour cells in 25 (67%) adenocarcinomas.
A, Kondi-Paphitis, B J, Addis
openaire   +2 more sources

Secretory meningioma with lipomatous component: case report

Brain Tumor Pathology, 1999
A case of meningioma coexisting with both lipomatous and secretory components, the latter characterized by hyaline inclusion bodies, is reported. The neuroradiological features of lipomeningioma are reevaluated, and the possible pathogenetic mechanisms of this unique combination in the present case are discussed.
H, Yamada, T, Hanada, S, Okuda, A, Yokota, J, Haratake   +4 more
openaire   +2 more sources

The structure of bovine secretory component

Veterinary Immunology and Immunopathology, 1987
Bovine secretory component (SC) has been cleaved with trypsin into a series of fragments and their N-terminal amino acid sequences have been determined. The close homology with the known sequence of human SC has enabled the sequential order of the fragments to be deduced. The results indicate that bovine SC consists of a single glycosylated polypeptide
openaire   +2 more sources

Characterization of the human secretory component gene promoter

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1997
Secretory Component (SC) is a receptor molecule implicated in the transepithelial transport of polymeric immunoglobulins. We have cloned and characterized the first exon, part of the first intron and 3500 bp of the upstream region of the gene and determined the transcription initiation region.
G, Verrijdt, J, Swinnen, B, Peeters, G, Verhoeven, W, Rombauts, F, Claessens   +5 more
openaire   +3 more sources

Human secretory component. II. Easy detection of abnormal amounts of combined secretory component in human sera

Journal of Immunological Methods, 1979
A simple method, allowing easy detection of abnormally increased sIgA levels is described. It consists in quantitation of combined SC by gel double diffusion, using appropriate anti-SC immune sera. The technical conditions, locating the threshold of sensitivity of precipitation at about 25 microgram/ml, a value higher than that found in normal sera ...
S, Iscaki, C, Geneste, S, d'Azambuja, J, Pillot   +3 more
openaire   +2 more sources

Studies on secretory component in digestive disease. IV. levels of serum secretory component in liver disease

Gastroenterologia Japonica, 1980
The levels of serum secretory component (SC), immunoglobulins, rheumatoid factor, HBs-antigen and HBs-antibody were determined in patients with liver disease, especially chronic liver disease. In chronic liver disease, decreases in serum SC were accompanied by increases in the titer of rheumatoid factor.
K, Kunishi, T, Arima, T, Yasuhara, J, Narumoto, K, Suwaki, H, Nagashima   +5 more
openaire   +2 more sources

Serum Secretory IgA and IgM and Free Secretory Component in IgA Nephropathy

Nephron, 1995
IgA nephropathy (IgAN) is characterized by the presence of IgA and C3 deposits in the mesangium. Mesangial IgA is mostly dimeric IgA1 with a J chain, lacking a secretory component. In view of the recent demonstration of elevated serum levels of secretory component and secretory IgA in liver disease and HIV infection associated with hyper-IgA, we ...
C M, Mole, E, Renoult, M C, Béné, E, Seillès, M, Kessler, J P, Revillard, G C, Faure   +6 more
openaire   +2 more sources

Uncoupling of the secretory pathways for IgA and secretory component by cholestasis

American Journal of Physiology-Gastrointestinal and Liver Physiology, 1987
Circulating polymeric immunoglobulin A (IgA) binds to secretory component (SC) on the surface of rat hepatocytes and is internalized and transported by vesicles to the canalicular membrane where the IgA-SC complex is secreted into bile. To further characterize this transport pathway, we examined the effects of bile flow reduction or transient bile ...
T M, Kloppel, T C, Hoops, D, Gaskin, M, Le   +3 more
openaire   +2 more sources

Secretory IgA, free secretory component and IgD in saliva of newborn infants

Early Human Development, 2001
To determine levels of secretory IgA (sIgA), free secretory component (FSC) and IgD in saliva of newborn infants at the age of 1 day and to evaluate the detection patterns, the influence of saliva flow and the relation to serum derived proteins.Seventy-three healthy newborn infants were studied.
Seidel, Bastian Manfred, Schubert, Simone, Schulze, Birgit, Borte, Michael   +3 more
openaire   +3 more sources