Results 251 to 260 of about 242,930 (301)

Canine Secretory Immunoglobulins: Identification of Secretory Component

The Journal of Immunology, 1970
Abstract Immunoglobulin A was demonstrated in canine tracheal secretions, saliva, tears, nasal secretions and colostrum. Another molecular species, presumably canine secretory component, was demonstrated in colostrum, tracheal secretions and tears.
J, Ricks, M, Roberts, R, Patterson
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Characterization of epitopes of human secretory component on free secretory component, secretory IgA, and membrane-associated secretory component.

The Journal of Immunology, 1984
Abstract We have compared the epitopes present in various forms of human secretory component by using a panel of hybridoma-derived antibodies elicited by immunizing mice with free secretory component (FSC) or secretory IgA (sIgA). Enzyme-linked immunosorbent binding assays (ELISA) were used to assess antibody binding to FSC- and SC ...
C S, Woodard, J B, Splawski, R M, Goldblum, R M, Denney   +3 more
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Mouse Secretory Component

1995
The receptor for polymeric immunoglobulins (plg-R) has already been extensively studied in many species, but not much in mice1, the most common laboratory animals. This study was conducted to isolate and characterize mouse secretory component (SC) and/or plg-R and to produce an antiserum allowing immunolocalization of mouse SC/pIg-R as well as the ...
P G, Pierre, X B, Havaux, A, Langendries, P J, Courtoy, K, Goto, P, Maldague, J P, Vaerman   +6 more
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Secretory Component in Human Ocular Tissues

American Journal of Ophthalmology, 1980
Lacrimal tissue and accessory lacrimal tissue from seven autopsy cases, lacrimal tissue from three patients undergoing orbital exploration, and biopsy specimens from conjunctiva of 14 subjects were examined for the presence and distribution of secretory component by three anti-secretory-component antisera.
M R, Allansmith, T E, Gillette
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Biochemical characterization of chicken secretory component

European Journal of Immunology, 1986
AbstractHuman dimeric IgA was injected i.v. into chickens whose bile was then collected. The human IgA which had been transported across the hepatocytes of the chicken was subsequently purified from the bile and shown to be associated with a protein of 80 kDa and pI 4.6, which reacted with rabbit antisera to chicken bile proteins but not with an ...
J V, Peppard, S M, Hobbs, L E, Jackson, M E, Rose, A P, Mockett   +4 more
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Carbohydrate moieties in human secretory component

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1999
Human secretory component has seven putative sites for N-linked glycosylation. From tryptic and Glu-C digests we have isolated peptides encompassing asparagines 65, 72, 117, 168, 403, 451 and 481. Analysis by on line HPLC-electrospray mass spectrometry indicated that these residues were fully glycosylated and that the major carbohydrate moieties were ...
G J, Hughes, A J, Reason, L, Savoy, J, Jaton, S, Frutiger-Hughes   +4 more
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Urinary secretory immunoglobulin A and free secretory component in pyelonephritis

American Journal of Kidney Diseases, 1995
The immune defense mechanisms of mucosal surfaces involve secretory immunoglobulin A (sIgA) antibodies and, to a lesser degree, other specific and nonspecific immune factors. These antibodies are dependent on a secretory component (SC) for their transmission through the epithelium. This SC is also secreted without Ig as free SC (FSC).
D, Greenwell, J, Petersen, A, Kulvicki, J, Harder, R, Goldblum, D E, Neal   +5 more
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Human secretory component—IV. Aggregation and fragmentation of of free secretory component

Immunochemistry, 1975
Abstract Most of the free secretory component (SC) present in a prepartum sample of colostrum had become degraded in vivo . Comparable degradation of partially purified SC from normal colostrum took place upon storage at 4°C. The major resulting fragment had a mol. wt of 35,000–42,000; it carried the A 2 antigenic determinant of SC, but lacked A 1
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Role of Secretory IgA, Secretory Component, and Eosinophils in Mucosal Inflammation

International Archives of Allergy and Immunology, 2000
Eosinophils and their products are important in the pathophysiology of allergic inflammation in mucosal tissues. Secretory component (SC) bound to IgA mediates transepithelial transport of IgA. As another biological activity of SC, we have reported that secretory IgA (sIgA) and SC preferentially activate human eosinophils.
Y, Motegi, H, Kita, M, Kato, A, Morikawa
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Ionic components of secretory cell surfaces in relation to secretory function

The Histochemical Journal, 1977
Rat pancreas was examined by ultrastructural cytochemical methods for localizing cations and anions, as well as polyanions and, more specifically, sulphated mucosubstance. Exceptionally abundant antimonate-precipitable cation was demonstrated between pancreatic acinar cells and at the base of the centro-acinar and other duct epithelial cells ...
T, Katsuyama, S S, Spicer
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