Results 121 to 130 of about 326,424 (312)

Phenylephrine increases tear cathepsin S secretion in healthy murine lacrimal gland acinar cells through an alternative secretory pathway

, 2021
Runzhong Fu, Srikanth Reddy Janga, Maria C. Edman, Sarah F. Hamm‐Alvarez   +3 more
openalex   +2 more sources

Small Nucleolar RNA Snord17 Promotes Self‐Renewal of Intestinal Stem Cells through Yy2 mRNA Export and Tead4 Activation

Advanced Science, EarlyView.
Snord17, through interaction with Thoc3, promotes nuclear export and translation of Yy2 mRNA in Snord17+/+ ISCs. The Yy2 protein subsequently binds the Tead4 promoter to promote its transcription, activating Hippo signaling, which is essential for ISC maintenance.
Peikang Zhang, Yuwei Xu, Yufei Lan, Zhen Xiong, Zhibin Yi, Runyuan Wu, Cunzhen Li, Ying Du, Hui Guo, Yingchi Yang, Zusen Fan   +10 more
wiley   +1 more source

Navigating the secretory pathway [PDF]

EMBO reports, 2002
Emmanuel G Reynaud, Jeremy C Simpson
openaire   +1 more source

Metabolic Reprogramming Driven by Trophoblasts and Decidual XCR1+PMN‐MDSC Crosstalk Controls Adverse Outcomes Associated With Advanced Maternal Age

Advanced Science, EarlyView.
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen, Yuxiong Guo, Qing Zhao, Jingping Liu, Shuyi Kuang, Zhengcong Huang, Chenlin Lv, Shuxiu Xu, Zekai Zhuang, Anyan Yang, Jing Li, Kai Wu, Yumei He   +12 more
wiley   +1 more source

MOESM6 of Effect of secretory pathway gene overexpression on secretion of a fluorescent reporter protein in Aspergillus nidulans

, 2016
Martin Schalén, Diana Chinyere Anyaogu, Jakob Blæsbjerg Hoof, Mhairi Workman   +3 more
openalex   +1 more source

A “Septide‐Sensitive” Receptor Is Not Involved in Tachykinin‐Mediated Secretory and Inositol Phosphate Responses in Rat Parotid Gland: Are Several Transduction Pathways Involved After the Stimulation of the NK₁ Receptor? [PDF]

, 1998
Claire Huleux, Annabel Berthier, B. Rossignol, C Dreux   +3 more
openalex   +1 more source

Decision letter: Pathogenic variants of sphingomyelin synthase SMS2 disrupt lipid landscapes in the secretory pathway

, 2022
Anant K. Menon
openalex   +1 more source

CircTspan3 Promotes Cartilage Development Through ANNEXIN A2‐Mediated Ferroptosis and Apoptosis Inhibition and Exosome‐Mediated Paracrine Signaling

Advanced Science, EarlyView.
This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan, Fengmei Zhang, Jiayan Zhong, Qian Gong, Nana Geng, Biao Kuang, Qiumei Lan, Miao Yi, Qiqi Zeng, Cheng Chen, Mengtian Fan, Chunliang Zhao, Deping Zeng, Yu Du, Mao Nie, Zhibiao Wang, Fengjin Guo   +16 more
wiley   +1 more source

Metalation and activation of Zn²⁺ enzymes via early secretory pathway-resident ZNT proteins. [PDF]

Biophys Rev (Melville), 2023
Kambe T, Wagatsuma T.
europepmc   +1 more source

Protein retention in yeast rough endoplasmic reticulum: expression and assembly of human ribophorin I. [PDF]

, 1990
The RER retains a specific subset of ER proteins, many of which have been shown to participate in the translocation of nascent secretory and membrane proteins. The mechanism of retention of RER specific membrane proteins is unknown.
Crowe, JS, Meyer, DI, Sanderson, CM
core