Results 261 to 270 of about 326,424 (312)
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Maturing secretory granules: Where secretory and endocytic pathways converge
Advances in Biological Regulation, 2021Secretory granules (SGs) are specialized organelles responsible for the storage and regulated release of various biologically active molecules from the endocrine and exocrine systems. Thus, proper SG biogenesis is critical to normal animal physiology.
Cheng-I Jonathan Ma +2 more
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Annexins in the secretory pathway
Cellular and Molecular Life Sciences (CMLS), 1997Among the multiplicity of roles suggested for proteins of the annexin family, those implicating these proteins in regulated exocytosis remain among the most convincing. Studies in this area of annexin biology have focused on annexin II, which because of its unusually low Ca(2+)-requirement for phospholipid-binding has many of the requisite properties ...
S R, Donnelly, S E, Moss
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Novel Secretory Pathways in Plasmodium?
Parasitology Today, 1999The secretion of proteins from intraerythrocytic stages of Plasmodium falciparum into the infected host cell is still poorly understood. A recent proposal that two distinct, mutually exclusive, secretory compartments may exist within the parasite cell has received much attention.
D, Mattei +3 more
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Proton Pumping in the Secretory Pathway
Journal of Membrane Biology, 2001Contains fulltext : 308741.pdf (Publisher’s version ) (Closed access)
Schoonderwoert, V.T., Martens, G.J.M.
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Morphodynamics of the Secretory Pathway
2004A careful scrutiny of the dynamics of secretory compartments in the entire eukaryotic world reveals many common themes. The most fundamental theme is that the Golgi apparatus and related structures appear as compartments formed by the act of transporting cargo. The second common theme is the pivotal importance for endomembrane dynamics of shifting back
Képès, François +2 more
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Quality control in the secretory pathway
Current Opinion in Cell Biology, 1995Whereas newly synthesized proteins that have acquired a properly folded and assembled structure are transported from the endoplasmic reticulum to their final destinations, incompletely folded and assembled proteins are, as a rule, retained and eventually degraded.
C, Hammond, A, Helenius
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Molecular dissection of the secretory pathway
Nature, 1992A combination of biochemistry in animal cell-free systems and genetics in yeast is revealing the molecular machinery of the secretory pathway of eukaryotes. Transporting vesicles have a simple coat structure and employ a general mechanism for fusion that is conserved in evolution.
J E, Rothman, L, Orci
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A NOVEL PATHWAY FOR SECRETORY PROTEINS?
Trends in Biochemical Sciences, 1990In eukaryotes, most proteins which are transported to the extracellular space, into mitochondria or into chloroplasts are synthesized as precursor polypeptides containing cleavable N-terminal signal or targeting sequences. We have searched the literature for proteins that are exported from the cytosol without being proteolytically processed.
MUESCH A. +5 more
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Neurotrophin secretory pathways and synaptic plasticity
Neurobiology of Aging, 2003Neurotrophins and synaptic activity work in conjunction during the process of synaptic plasticity. Both are required to stabilize new synaptic structures and the loss of either can lead to cognitive impairments, as new information cannot be stored efficiently or later recalled.
Kuei-Cheng, Lim +2 more
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The perplexing PEXEL protein secretory pathway
Nature Microbiology, 2018Plasmodium parasites possess a unique PEXEL sorting pathway to deliver secretory proteins into the host cells in which they reside. A new study shows the existence of independent sorting/entry complexes to detect and deliver PEXEL proteins into the parasite endoplasmic reticulum.
Pool, Martin, Russo, Ilaria
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