Results 101 to 110 of about 250,111 (340)

Cystatin A promotes the antitumor activity of T helper type 1 cells and dendritic cells in murine models of pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti   +8 more
wiley   +1 more source

Riemannian Submersions Need Not Preserve Positive Ricci Curvature [PDF]

open access: yesarXiv, 2012
If $\pi :M\rightarrow B$ is a Riemannian Submersion and $M$ has positive sectional curvature, O'Neill's Horizontal Curvature Equation shows that $B$ must also have positive curvature. We show there are Riemannian submersions from compact manifolds with positive Ricci curvature to manifolds that have small neighborhoods of (arbitrarily) negative Ricci ...
arxiv  

On Sectional Curvatures and Characteristic of Homogeneous Spaces [PDF]

open access: yesProceedings of the American Mathematical Society, 1966
where cn is the volume of the Euclidean unit n-sphere, Yn the nth sectional curvature (see the definition (2) below) and co the volume element of the Riemannian structure of X. It is a still open question, whether the fact that the usual sectional curvature (second order sectional curvature) 72 has a constant sign for all plane sections, has some ...
Werner Greub, Phillippe Tondeur
openaire   +2 more sources

Clinical significance of stratifying prostate cancer patients through specific circulating genes

open access: yesMolecular Oncology, EarlyView.
We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian   +12 more
wiley   +1 more source

On curvature tensors of Norden and metallic pseudo-Riemannian manifolds

open access: yesComplex Manifolds, 2019
We study some properties of curvature tensors of Norden and, more generally, metallic pseudo-Riemannian manifolds. We introduce the notion of J-sectional and J-bisectional curvature of a metallic pseudo-Riemannian manifold (M, J, g) and study their ...
Blaga Adara M., Nannicini Antonella
doaj   +1 more source

Moments of Sectional Curvature

open access: yes, 2017
The sectional curvature of a compact Riemannian manifold M can be seen as a random variable on the Grassmann bundle of 2-planes in TM endowed with the Fubini-Study volume density. In this article we calculate the moments of this random variable by integrating suitable local Riemannian invariants and discuss the distribution of the sectional curvature ...
openaire   +2 more sources

Riemannian Manifolds with Positive Sectional Curvature [PDF]

open access: yes, 2014
This is a survey of recent results on manifolds with positive curvature from a series of lecture given in Guanajuato, Mexico in 2010. It also contains some hitsorical comments.
openaire   +2 more sources

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

open access: yesMolecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien   +7 more
wiley   +1 more source

Complete spacelike hypersurfaces with positive r-th mean curvature in a semi-Riemannian warped product

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2015
In this paper, by supposing a natural comparison inequality on the positive r-th mean curvatures of the hypersurface, we obtain some new Bernstein-type theorems for complete spacelike hypersurfaces immersed in a semi-Riemannian warped product of constant
Wang Yaning, Liu Ximin
doaj   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

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