Results 101 to 110 of about 28,093 (313)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

On totally umbilical CR-submanifolds of a Kaehler manifold

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1993
Let M be a compact 3-dimensional totally umbilical CR-submanifold of a Kaehler manifold of positive holomorphic sectional curvature. We prove that if the length of the mean curvature vector of M does not vanish, then M is either diffeomorphic to S3 or ...
M. A. Bashir
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Lorentzian Beltrami-Euler formula and generalized Lorentzian Lamarle formila in R_1^n

open access: yesLe Matematiche, 2009
In this paper, the sectional curvature of non-degenerate tangent sections of time-like ruled surface with the central ruled surface in n-dimensional Minkowski space, R_1^n  is studied. The relationship between normal sectional curvature and the principal
Soley Ersoy, Murat Tosun
doaj  

On the Topological Classification of Four-Dimensional Steady Gradient Ricci Solitons with Nonnegative Sectional Curvature

open access: yesMathematics
In this paper, we study the topology of steady gradient Ricci solitons with nonnegative sectional curvature. We apply a characterization theorem for the fundamental group of a positively curved steady gradient Ricci soliton that admits a critical point ...
Yuehan Hao
doaj   +1 more source

Remarks on symplectic sectional curvature

open access: yesDifferential Geometry and its Applications, 2017
In [11], I. M. Gelfand, V. Retakh, and M. Shubin defined the symplectic sectional curvature of a torsion-free connection preserving a symplectic form. The present article defines the corresponding notion of constant symplectic sectional curvature and characterizes this notion in terms of the curvature tensor of the symplectic connection and its ...
openaire   +3 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Conharmonically flat and conharmonically symmetric warped product manifolds

open access: yesAIP Advances
This article presents characterizations of warped product manifolds based on the flatness and symmetry of the conharmonic curvature tensor. It is proved that when a warped product manifold is conharmonically flat, both the base and fiber manifolds ...
Abdallah Abdelhameed Syied   +2 more
doaj   +1 more source

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