Results 81 to 90 of about 1,470,963 (294)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Generalized pseudo Ricci symmetric manifolds with semi-symmetric metric connection

open access: yesKuwait Journal of Science, 2014
In this paper, firstly an example of a manifold with almost constant curvature and nearly quasi constant curvature which is neither quasi Einstein nor nearly quasi Einstein is given.
SEZGIN ALTAY DEMIRBAG
doaj  

Complete spacelike hypersurfaces with positive r-th mean curvature in a semi-Riemannian warped product

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2015
In this paper, by supposing a natural comparison inequality on the positive r-th mean curvatures of the hypersurface, we obtain some new Bernstein-type theorems for complete spacelike hypersurfaces immersed in a semi-Riemannian warped product of constant
Wang Yaning, Liu Ximin
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

On area comparison and rigidity involving the scalar curvature [PDF]

open access: yes
In this thesis we study the effects of lower bounds for the curvature of a Riemannian manifold M on the geometry and topology of closed, minimal hypersurfaces.
Moraru, Vlad
core  

Curvature and topology dependency of the cosmological spectra

open access: yesResults in Physics, 2019
In this article we investigate dependency of two important cosmological random fields defined on spatial slices of the FLRW universe and their spectra on the geometry and topology of the background universe.
Ali A. Asgari   +2 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Beltrami-Meusnier formulas of generalized semi ruled surfaces in semi Euclidean space

open access: yesKuwait Journal of Science, 2014
In this paper, we study the sectional curvatures of the generalized semi ruled surfaces in semi Euclidean space   The first fundamental form and the metric coefficients of the generalized semi ruled surfaces are calculated and in these regards ...
MAHMUT AKYIG١IT   +2 more
doaj  

A basic inequality for submanifolds in a cosymplectic space form

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2003
For submanifolds tangent to the structure vector field in cosymplectic space forms, we establish a basic inequality between the main intrinsic invariants of the submanifold, namely, its sectional curvature and scalar curvature on one side; and its main ...
Jeong-Sik Kim, Jaedong Choi
doaj   +1 more source

Remarks on Sectional Curvature of an Indefinite Metric [PDF]

open access: yesProceedings of the American Mathematical Society, 1983
The properties of sectional curvature for an indefinite metric are further studied following the works of R. S. Kulkarni, L. Graves and the author, S. G. Harris, and M. Dajczer and the author.
openaire   +1 more source

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