Results 71 to 80 of about 1,470,963 (294)
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Nasal and temporal curvatures of lamina CRIBROSA in myopic eyes
Scientific Reports, 2022 Little is known about the myopic characteristics of lamina cribrosa (LC) curvature. As such, we investigated nasal and temporal LC curvatures in myopia.
Sooyeon Choe +6 more
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
The spinor representation of constant mean curvature one surfaces in the Hyperbolic space [PDF]
, 1970 We review and comment on some aspects of the spinor representation for constant mean curvature one surfaces in hyperbolic space developed by Bobenko-Pavlyukevich-Springborn in [1].
Nicolodi, Lorenzo +4 more
core +1 more source
A Novel Approach for Evaluating Seismic Performance of Frame-Type Underground Structures
BuildingsThis paper examines the seismic performance evaluation methodology for underground structures. Through analysis of seismic damage and failure characteristics of underground structures, this study proposes a novel evaluation approach for frame-type ...
Zhong-Yang Yu +5 more
doaj +1 more source
On Einstein Manifolds of Positive Sectional Curvature
Annals of Global Analysis and Geometry, 1999 Let (M,g) be a compact oriented Einstein 4-manifold. If M has positive intersection form and g has non-negative sectional curvature, we show that, up to rescaling and isometry, (M,g) is CP2, equipped with its standard Fubini-Study metric.
Gursky, Matthew J., LeBrun, Claude
openaire +2 more sources
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Қарағанды университетінің хабаршысы. Математика сериясыIn the present paper sets related to invariant Riemannian metrics of positive sectional and (or) Ricci curvature on generalized Wallach spaces are considered.
N.A. Abiev
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On curvature tensors of Norden and metallic pseudo-Riemannian manifolds
Complex Manifolds, 2019 We study some properties of curvature tensors of Norden and, more generally, metallic pseudo-Riemannian manifolds. We introduce the notion of J-sectional and J-bisectional curvature of a metallic pseudo-Riemannian manifold (M, J, g) and study their ...
Blaga Adara M., Nannicini Antonella
doaj +1 more source