Results 91 to 100 of about 1,470,963 (294)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

TEXAS FIELD CROPS: ESTIMATION WITH CURVATURE [PDF]

Some implications of theory are easily maintained in econometric estimation, but computational costs of maintaining curvature properties (sufficient for existence of an optimal solution) have often proved prohibitive.
Shumway, C. Richard, Talpaz, Hovav, Alexander, William P.   +2 more
core  

Ricci Flow Does Not Necessarily Preserve Positive Radial Sectional Curvature [PDF]

, 2022
We exhibit a one-parameter family of smooth Riemannian metrics on the four-dimensional sphere with strictly positive radial sectional curvature that loses this property when evolved through the Ricci flow.
Ta, Ryan Joseph
core   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

A Kähler Einstein structure on the tangent bundle of a space form

International Journal of Mathematics and Mathematical Sciences, 2001
We obtain a Kähler Einstein structure on the tangent bundle of a Riemannian manifold of constant negative curvature. Moreover, the holomorphic sectional curvature of this Kähler Einstein structure is constant.
Vasile Oproiu
doaj   +1 more source

Casorati Inequalities for Statistical Submanifolds in Kenmotsu Statistical Manifolds of Constant ϕ-Sectional Curvature with Semi-Symmetric Metric Connection. [PDF]

Entropy (Basel), 2022
Decu S, Vîlcu GE.
europepmc   +1 more source

On the Sectional Curvature of Holomorphic Curvature Operators [PDF]

Proceedings of the American Mathematical Society, 1981
Guerrero, Ignacio, Zoltek, Stanley M.
openaire   +2 more sources

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Almost Kenmotsu $f$-manifolds

Karpatsʹkì Matematičnì Publìkacìï, 2015
In this paper, we consider a generalization of almost Kenmotsu f-manifolds. We get basic Riemannian curvature, sectional curvatures and scalar curvature properties such type manifolds. Finally, we give two examples to clarify some our results.
Y.S. Balkan, N. Aktan
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source