Results 101 to 110 of about 1,568,392 (257)

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Euler-Poincaré characteristic and higher order sectional curvature. I

open access: yes, 1988
The following long-standing conjecture of H. Hopf is well known. Let M M be a compact orientable Riemannian manifold of even dimension n ⩾ 2 n \geqslant 2 .
Chuan-Chih Hsiung   +1 more
core   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

SECTIONAL CURVATURE DUCTILTY OF REINFORECD CONCRETE COLUMNS UNDER LARGE INELASTIC DEFORMATION

open access: yesJournal of Engineering
A mathematical model is developed to express stress-strain relationship of normal-strength concrete confined by transverse reinforcement. The sectional ductility analysis on rectangular reinforced concrete columns is performed under axial load ...
Raad K. Al-Azzawi
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

On the sectional curvature of compact hypersurfaces

open access: yes, 1990
We establish a sufficient condition for compact hypersurfaces of a complete riemannian manifold to be spherical. It is well known, from the works of Jacobowitz, Jorge and Koutroufiotis, and others, that the maximum sectional curvature of such ...
Leslie Coghlan, Yoe Itokawa
core   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Lorentzian Beltrami-Euler formula and generalized Lorentzian Lamarle formila in R_1^n

open access: yesLe Matematiche, 2009
In this paper, the sectional curvature of non-degenerate tangent sections of time-like ruled surface with the central ruled surface in n-dimensional Minkowski space, R_1^n  is studied. The relationship between normal sectional curvature and the principal
Soley Ersoy, Murat Tosun
doaj  

Conharmonically flat and conharmonically symmetric warped product manifolds

open access: yesAIP Advances
This article presents characterizations of warped product manifolds based on the flatness and symmetry of the conharmonic curvature tensor. It is proved that when a warped product manifold is conharmonically flat, both the base and fiber manifolds ...
Abdallah Abdelhameed Syied   +2 more
doaj   +1 more source

On the Topological Classification of Four-Dimensional Steady Gradient Ricci Solitons with Nonnegative Sectional Curvature

open access: yesMathematics
In this paper, we study the topology of steady gradient Ricci solitons with nonnegative sectional curvature. We apply a characterization theorem for the fundamental group of a positively curved steady gradient Ricci soliton that admits a critical point ...
Yuehan Hao
doaj   +1 more source

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