Results 61 to 70 of about 15,450 (291)

A new high-resolution geomagnetic field model for southern Africa

open access: yesSouth African Journal of Science
Earth’s magnetic field is a dynamic, changing phenomenon. The geomagnetic field consists of contributions from several sources, of which the main field originating in Earth’s core makes up the bulk.
Amore E. Nel   +3 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Secular variation on the territory of the Czech Republic and reduction of the magnetic survey to the epoch 2010.5

open access: yesAnnals of Geophysics, 2013
A recent stage of the magnetic surveying activities in the Czech Republic was started in the fifties by setting up a basic network of the first order. It consists of 199 points.
Pavel Hejda   +2 more
doaj   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Geomagnetic secular variation since 1901 [PDF]

open access: yesDeep Sea Research Part B. Oceanographic Literature Review, 1981
Summary. All available annual means, from the world-wide network of magnetic observatories, of north intensity (X), east intensity (Y) and vertical intensity (Z) from 1901 to 1977 are subjected to spherical harmonic analysis to obtain 38 models of the Earth's geomagnetic field at two-year intervals.
openaire   +2 more sources

Elements of a Theory of Religious-Secular Competition

open access: yesPolítica & Sociedade, 2017
This article presents basic elements of a theory of religious-secular competition on the individual level. The theory claims that individuals in many societies may choose between religious and secular options, creating a situation of competition between
Jörg Stolz, Pascal Tanner
doaj   +1 more source

Secular variation of the geocenter [PDF]

open access: yesJournal of Geophysical Research: Solid Earth, 2000
The degree 1 deformations of Earth induced by a surface load are computed, in a reference frame related to the center of mass of the planet, using a theoretical approach (Love number formalism), at secular timescale, where Earth has a viscoelastic behavior.
openaire   +1 more source

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