Results 31 to 40 of about 34,258 (223)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

PROSPECTIVE RESEARCH DIRECTIONS IN THE ELECTRONIC COMMUNICATIONS INDUSTRY

open access: yesInformation and Telecommunication Sciences
Background. At the present stage, electronic communications must provide: ultra-fast data exchange between production systems, which increases productivity and safety; the use of robotic systems and artificial intelligence to support people in production
Serhii Kravchuk, Iryna Kravchuk
doaj   +1 more source

A Secure Protocol for Remote-Code Integrity Attestation of Embedded Systems: The CSP Approach

open access: yesIEEE Access, 2019
No doubt, a person of modern society relying on Embedded Systems (ESs) has increased rapidly and the era of digital machines is gaining popularity among users and also systems providers.
Abdo Ali A. Al-Wosabi, Zarina Shukur
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Concept, connotation, technology and development status of Web 3.0

open access: yes工程科学学报, 2023
Web 3.0 has widely piqued the interest of academia and industry as the next-generation internet. Therefore, this study analyzes the development process and status of Web 3.0 from the perspectives of countries (policies, companies, and products ...
Lei XU, Sha LI, Huan-sheng NING
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Improving data security and privacy in sports health monitoring through blockchain

open access: yesSystems and Soft Computing
With the increasing attention to health and fitness in modern society, the demand for reliable sports health monitoring systems is also growing. However, traditional systems often face key issues related to data security, privacy protection, and ...
Xiaochun Yuan
doaj   +1 more source

Multi-Factor Authentication: A Survey

open access: yesCryptography, 2018
Today, digitalization decisively penetrates all the sides of the modern society. One of the key enablers to maintain this process secure is authentication.
Aleksandr Ometov   +5 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Digital Social Identity Management: Current Status, Problems, and Countermeasures

open access: yes中国工程科学
Currently, China is undergoing a comprehensive transition toward a digital society, which has placed renewed emphasis on the need for robust national-level digital management capabilities.
Yu Rui   +5 more
doaj   +1 more source

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