Results 41 to 50 of about 37,877 (256)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Concept, connotation, technology and development status of Web 3.0

open access: yes工程科学学报, 2023
Web 3.0 has widely piqued the interest of academia and industry as the next-generation internet. Therefore, this study analyzes the development process and status of Web 3.0 from the perspectives of countries (policies, companies, and products ...
Lei XU, Sha LI, Huan-sheng NING
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Improving data security and privacy in sports health monitoring through blockchain

open access: yesSystems and Soft Computing
With the increasing attention to health and fitness in modern society, the demand for reliable sports health monitoring systems is also growing. However, traditional systems often face key issues related to data security, privacy protection, and ...
Xiaochun Yuan
doaj   +1 more source

Multi-Factor Authentication: A Survey

open access: yesCryptography, 2018
Today, digitalization decisively penetrates all the sides of the modern society. One of the key enablers to maintain this process secure is authentication.
Aleksandr Ometov   +5 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

A Secure Cooperative Sensing Protocol for Cognitive Radio Networks [PDF]

open access: yes, 2010
Cognitive radio networks sense spectrum occupancy and manage themselves to operate in unused bands without disturbing licensed users. Spectrum sensing is more accurate if jointly performed by several reliable nodes. Even though cooperative sensing is an
Rifà Pous, Helena   +1 more
core  

Digital Social Identity Management: Current Status, Problems, and Countermeasures

open access: yes中国工程科学
Currently, China is undergoing a comprehensive transition toward a digital society, which has placed renewed emphasis on the need for robust national-level digital management capabilities.
Yu Rui   +5 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Integrating security and usability into the requirements and design process [PDF]

open access: yes, 2006
According to Ross Anderson, 'Many systems fail because their designers protect the wrong things or protect the right things in the wrong way'. Surveys also show that security incidents in industry are rising, which highlights the difficulty of designing ...
Sasse, MA   +5 more
core  

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