Results 111 to 120 of about 1,445,751 (341)

Evaluation of fostering network Scottish care mentoring projects [PDF]

open access: yes, 2005
Looked after children and young people are some of the most vulnerable in our society. For Scotland’s Children highlighted the ‘continuing failure of many local authorities as ‘corporate parents’ to provide these young people with the care and education ...
Cadman, M., Hunter, L., Kendrick, A.
core  

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Adjusting the volume: reflections on engagement with autistic young people living in secure care

open access: yesScottish Journal of Residential Child Care
In undertaking a doctoral research project looking at the impact of Scottish secure care experience on the identity constructions of autistic young people, I experienced a number of unexpected challenges with engagement.
Charlotte Wilson
doaj   +1 more source

Characteristics and Pathways of Long-Stay Patients in High and Medium Secure Settings in England; A Secondary Publication From a Large Mixed-Methods Study

open access: yesFrontiers in Psychiatry, 2018
Background: Many patients experience extended stays within forensic care, but the characteristics of long-stay patients are poorly understood.Aims: To describe the characteristics of long-stay patients in high and medium secure settings in England.Method:
Birgit A. Völlm   +11 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Words into action: bridging the gap between theory and practice when supporting young people in care

open access: yesScottish Journal of Residential Child Care
The authors elucidate Johnstone's ABC Formulation Framework and 6D model for understanding and intervening with young people who display distressed behaviour.
Olivia Roles, Lorraine Johnstone
doaj   +1 more source

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