Results 111 to 120 of about 1,456,577 (296)

Characteristics and Pathways of Long-Stay Patients in High and Medium Secure Settings in England; A Secondary Publication From a Large Mixed-Methods Study

Frontiers in Psychiatry, 2018
Background: Many patients experience extended stays within forensic care, but the characteristics of long-stay patients are poorly understood.Aims: To describe the characteristics of long-stay patients in high and medium secure settings in England.Method:
Birgit A. Völlm, Birgit A. Völlm, Rachel Edworthy, Nick Huband, Emily Talbot, Shazmin Majid, Jessica Holley, Vivek Furtado, Vivek Furtado, Tim Weaver, Ruth McDonald, Conor Duggan   +11 more
doaj   +1 more source

Exploration of adverse patterns of placement of young people in secure care: The unwanted child? [PDF]

Crim Behav Ment Health, 2022
Smith JG, Bartlett A, Hales H.
europepmc   +1 more source

Maximizing Academic Success for Foster Care Students: A Trauma-Informed Approach

, 2017
Children in foster care have experienced significant trauma due to the loss of primary attachment figures and the circumstances associated with that loss. Children who have suffered trauma generally present with cognitive, social, physical, and emotional
Berardi, Anna A, PhD., Morton, Brenda M.
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Feel what you feel: effects of Reiki on young people in secure and residential childcare?

Scottish Journal of Residential Child Care
Action research was used to examine the potential of Reiki as a valid treatment in support of trauma recovery for young people in residential and secure care in Scotland.
Abbi Jackson
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Security in Cloud Health Care

International Journal of Recent Technology and Engineering (IJRTE), 2019
Cloud computing plays vital role in various services to the users. The application of cloud computing includes usage in business, media transmission, banking, health care, military application, insurance, wireless communication, etc. One such application using Cloud computing is health care. The patient health history is very significant for diagnostic
J.Rama Prabha*, S. Prabakaran
openaire   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

A national survey of current discharge planning and aftercare arrangement practices for those returned to prison from secure psychiatric services in England and Wales

BJPsych Open
Background Little is known about the transition process for those returned to prison following treatment in secure psychiatric services. This study is the first internationally to explore the process of discharge/aftercare planning for this population.
Sarah Leonard, Jana Bowden, Matilda Minchin, Ruth McDonald, Neil Allen, Jane Senior, Jennifer Shaw   +6 more
doaj   +1 more source