Results 101 to 110 of about 3,620,659 (295)

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

Molecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis, Tereza Buchtová, Jirina Bartkova, Marie Lund Bay, Christoffer Lynge Halvorsen, Zuzana Machacova, Zdenek Skrott, Martin Mistrik, Ekaterina Dulina, Miguel Andujar‐Sanchez, Estrid Høgdall, Tine Henrichsen Schnack, Claus Høgdall, Berit Jul Mosgaard, Marie Boennelycke, Jacob Brink Laursen, Allan Jensen, Susanne K. Kjær, Tuula Kallunki, Robert Strauss, Jiri Bartek   +20 more
wiley   +1 more source

Establishing Performance Baselines for Secure Software Development

IET Information Security
The COVID-19 pandemic has impacted the world, prompting a shift toward remote work and stay-at-home economies, altering routines for individuals and businesses.
Ying-Ti Tsai, Chung-Ho Wang, Yung-Chia Chang, Lee-Ing Tong   +3 more
doaj   +1 more source

Software Development Initiatives to Identify and Mitigate Security Threats - Two Systematic Mapping Studies

CLEI Electronic Journal, 2016
Software Security and development experts have addressed the problem of building secure software systems. There are several processes and initiatives to achieve secure software systems.
Paulina Silva, René Noël, Santiago Matalonga, Hernán Astudillo, Diego Gatica, Gastón Marquez   +5 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Secure Feature Driven Development (SFDD) Model for Secure Software Development

, 2014
This paper introduces an enhanced Feature Driven Development (FDD) model for secure software development. In fact, the enhanced model is based on our previous study and its findings which concluded that existing FDD poses limitations to develop secure ...
Ghani, Imran, Firdaus, Adila, Seung, Ryul Jeong   +2 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Secure Software Engineering Education: Knowledge Area, Curriculum and Resources

Journal of Cybersecurity Education, Research & Practice, 2016
This paper reviews current efforts and resources in secure software engineering education, with the goal of providing guidance for educators to make use of these resources in developing secure software engineering curriculum.
Xiaohong Yuan, Li Yang, Bilan Jones, Huiming Yu, Bei-Tseng Chu   +4 more
doaj  

TriTrust: Risk-Aware Three-Factor Trust Fusion for Secure UAV Handover Admission

Mathematics
Cooperative unmanned aerial vehicle (UAV) swarms require secure transaction-level admission decisions when tasks, relay roles, control privileges, or mission assets are transferred between aircraft.
Mustafa Ghaleb, Zaafir Riaz, Radhwan A. Saleh, Zead Saleh, Ibrahim Althamary, Sajjad Ahmad Khan, Kerem Küçük, Hamdi Altaheri   +7 more
doaj   +1 more source