Effectiveness of Hydroalcoholic Seed Extract of Securigera securidaca on Pancreatic Local Renin-Angiotensin System and Its Alternative Pathway in Streptozotocin-Induced Diabetic Animal Model [PDF]
Oxidative Medicine and Cellular Longevity, Volume 2023, Issue 1, 2023., 2023 Background. Available data suggest inhibition of the pancreatic local‐renin‐angiotensin system (RAS) reduces tissue complications of diabetes. The purpose of the present study was to investigate the effect of hydroalcoholic seed extract of Securigera securidaca (S. securidaca) (HESS) on the pancreatic local‐RAS and its alternative pathway.
Fatemeh Khomari +8 more
wiley +3 more sources
Evaluation of serum pro/anti-angiogenic biomarkers in hyperglycemic rats treated with Securigera securidaca seeds, alone and in combination with Glibenclamide [PDF]
Journal of Cardiovascular and Thoracic ResearchIntroduction: Herbal medicines are commonly used by many people with diabetes in addition to standard treatment. Plants contain numerous known and unknown compounds that may exacerbate or ameliorate diabetes complications.
Elham Bahreini +3 more
doaj +3 more sources
Effects of Securigera securidaca (L.) Degen & Dorfl seed extract combined with glibenclamide on paraoxonase1 activity, lipid profile and peroxidation, and cardiovascular risk indices in diabetic rats [PDF]
BioImpacts, 2020 Introduction: Seeds of Securigera securidaca (L.) Degen & Dorfl are rich in flavonoids and phenolic acids which have potent biological effects. The current study was undertaken to evaluate the effects of hydroalcoholic extract of S.
Shahin Alizadeh-Fanalou +5 more
doaj +2 more sources
Effect of Securigera Securidaca Seed on the Gene Expression of Pulmonary Hypertensive Broiler Chickens Induced by Cool Temperature and High-Altitude [PDF]
Poultry Science Journal, 2019 Securigera securidaca (Fabaceae) or goat pea is growing wild in West Asia, Europe and Africa as an annual herb. In Persian, it is called “Gandeh Talkheh”. The seeds of goat pea are applied in the traditional medicine to treat different dysfunctions e.g.,
Ahmadipour B, Kalantar M, Hassanpour H
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Antifungal effect of the effect of Securigera securidaca L. vaginal gel on Candida species [PDF]
Current Medical Mycology, 2019 Background and Purpose: Candida species are opportunistic fungi, capable of causing acute and chronic infections in the gastrointestinal tract, vagina, and oral mucosa, among which Candida albicans is the most important species. The Securigera securidaca
Atefeh Raesi Vanani +4 more
doaj +2 more sources
Advanced Biomedical Research, 2015 Background: Hyperlipidemia is an associated complication of diabetes mellitus. Lowering of serum lipid levels seems to be associated with a decrease in the risk of vascular disease and related complications.
Ziba Rajaei +4 more
doaj +2 more sources
Sub-acute toxicity profile of methanolic leaf extract of Securidaca longipedunculata in rats
UMYU Journal of Microbiology Research, 2019 This study investigates the toxicological profile of Securidaca longipedunculata in rats. Sub-acute toxicity study was conducted by oral administration of the extracts to rats at daily doses of 25, 50 and 100mg/kg body weight for 28 days.
Sadiq, F. U., Abalaka, M. E., Babayi, H.
doaj +3 more sources
Pollen and tapetal development in Securidaca longepedunculata
South African Journal of Botany, 1985 Pollen and tapetal development in Securidaca longepedunculata Fresen. (Polygalaceae) were examined at light microscopic and ultrastructural levels. The secretory tapetum is persistent and its complete degeneration occurs only during the mature spore stage.
Hester. Coetzee, P.J. Robbertse
openalex +2 more sources
Molecular docking and ADMET profiling of xanthones from Securidaca longepedunculata targeting oxidative stress in hypertension [PDF]
Discover ChemistryHypertension remains a major global health challenge, with oxidative stress playing a pivotal role in its pathogenesis and complications. In this study, six naturally-occurring xanthones isolated from Securidaca longepedunculata roots were evaluated for ...
Janvier Hinmara Tina +9 more
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پژوهشهای بذر ایران, 2016 In order to determinate the cardinal temperatures and investigate the effect of temperature on seed germination and seedling growth of Securigera securidaca, a study was conducted in a completely randomized design with 8 temperature treatments (5, 10, 15,
Zeinab Alipoor, Sohrab Mahmodi
doaj +3 more sources