Results 161 to 170 of about 5,783 (206)
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1994
Abstract The first alleles of secY were isolated as suppressors of signal sequence mutations and are designated prlA alleles4. Starting with a strain that was dextrin negative due to a mutation in the signal sequence of LamB (maltoporin), these suppressors were identified following selection for the ability to use dextrin as a carbon ...
A M Flower, T J Silhavy
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Abstract The first alleles of secY were isolated as suppressors of signal sequence mutations and are designated prlA alleles4. Starting with a strain that was dextrin negative due to a mutation in the signal sequence of LamB (maltoporin), these suppressors were identified following selection for the ability to use dextrin as a carbon ...
A M Flower, T J Silhavy
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Proceedings of the Workshop on Open Source and Design of Communication, 2013
Nowadays the organizations need to increase the efficiency rate of the service support, responding faster occurrences (e.g. in internal support like help-desk or end user support). The use of Knowledge Management (KM) platforms is becoming a solution adopted by most organizations.
Nuno Sousa +2 more
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Nowadays the organizations need to increase the efficiency rate of the service support, responding faster occurrences (e.g. in internal support like help-desk or end user support). The use of Knowledge Management (KM) platforms is becoming a solution adopted by most organizations.
Nuno Sousa +2 more
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Biochimie, 1997
Protein translocation across the plasma membrane of E coli is facilitated by Sec factors, including the membrane-embedded SecYEG subunit and the SecA ATPase. Although there is complete agreement that SecA is essential for protein translocation, some publications question the essentialness of SecY.
Tohru Yoshihisa, T Taura
exaly +3 more sources
Protein translocation across the plasma membrane of E coli is facilitated by Sec factors, including the membrane-embedded SecYEG subunit and the SecA ATPase. Although there is complete agreement that SecA is essential for protein translocation, some publications question the essentialness of SecY.
Tohru Yoshihisa, T Taura
exaly +3 more sources
Reconstitution of the SecY Translocon in Nanodiscs
2010Secretory proteins are transported across the bacterial envelope using a membrane protein complex called the SecY channel or translocon. Major advances in understanding this transporter have been accomplished with methods including purification, crystallization, and reconstitution of the translocation reaction in vitro.
Kush, Dalal, Franck, Duong
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PROTEIN TRANSLOCATION BY THE SEC61/SECY CHANNEL
Annual Review of Cell and Developmental Biology, 2005The conserved protein-conducting channel, referred to as the Sec61 channel in eukaryotes or the SecY channel in eubacteria and archaea, translocates proteins across cellular membranes and integrates proteins containing hydrophobic transmembrane segments into lipid bilayers.
Andrew R, Osborne +2 more
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2007
The Southeast Europe Cooperative Initiative (SECI) was viewed by many at its inception at the end of 1996 as a rather insignificant attempt to knit together countries that throughout history had not gotten along particularly well. This brainchild of Ambassador Richard Schifter looked puny if compared to the multi-billion dollar effort to repair the ...
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The Southeast Europe Cooperative Initiative (SECI) was viewed by many at its inception at the end of 1996 as a rather insignificant attempt to knit together countries that throughout history had not gotten along particularly well. This brainchild of Ambassador Richard Schifter looked puny if compared to the multi-billion dollar effort to repair the ...
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Two-step insertion at the SecY translocon
Nature Structural & Molecular Biology, 2012SecY and Sec61 translocons mediate the orderly insertion of transmembrane segments into the lipid bilayer during membrane-protein biogenesis. Reporting in this issue, Ismail et al. now use a SecM-based molecular force sensor to show that the translocon exerts a pulling force on the nascent chain that is capable of mechanical action at two distinct ...
Soo Jung, Kim, William R, Skach
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Identification of Leishmania selenoproteins and SECIS element
Molecular and Biochemical Parasitology, 2006Selenoproteins result from the incorporation of selenocysteine (Sec-U) at an UGA-stop codon positioned within a gene's open reading frame and directed by selenocysteine insertion sequence (SECIS) elements. Although the selenocysteine incorporation pathway has been identified in a wide range of organisms it has not yet been reported in the ...
A, Cassago +8 more
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2001
The 3′-untranslated regions (UTRs) of selenoprotein mRNAs contain a stable stem-loop termed the selenocysteine insertion sequence (SECIS) element. Among the trans-acting factors that are thought to be required for selenocysteine (Sec) insertion are RNA binding proteins that interact with the SECIS element. In addition to several proteins which bind non-
Paul R. Copeland, Donna M. Driscoll
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The 3′-untranslated regions (UTRs) of selenoprotein mRNAs contain a stable stem-loop termed the selenocysteine insertion sequence (SECIS) element. Among the trans-acting factors that are thought to be required for selenocysteine (Sec) insertion are RNA binding proteins that interact with the SECIS element. In addition to several proteins which bind non-
Paul R. Copeland, Donna M. Driscoll
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SecY variants that interfere with Escherichia coli protein export in the presence of normal secY
Molecular Microbiology, 1992SummaryAs an approach for studying how SecY, an integral membrane protein translocation factor of Escherichia coli, interacts with other protein molecules, we isolated a dominant negative mutation, secY‐d1, of the gene carried on a plasmid. The mutant plasmid severely inhibited export of maltose‐binding protein and less severely of OmpA, when ...
T, Shimoike +4 more
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