Results 121 to 130 of about 242,778 (310)
Complications of conscious sedation: causes and management
, 2017 : Conscious sedation is a common treatment modality for patients with dental anxiety. In adults, intravenous sedation using Midazolam is the most common method of conscious sedation. For inhalational sedation, Nitrous Oxide and Oxygen are used frequently.
Tina Halai +3 more
core +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Canadian Medical Association Journal, 2014 Romayne, Gallagher, Caroline, Baldwin
openaire +5 more sources
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Improving the Safety of Pediatric Sedation: Human Expertise, Technology, and System Redesign
Recent years have seen important improvements in the safety of many areas of health care. However, evidence would suggest that the practice of pediatric sedation outside of the operating room is an area where unaddressed complexities and risks in care ...
Merry, Alan +5 more
core +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
BMC NursingBackground Patient safety is a major priority in intensive care units (ICUs), particularly among mechanically ventilated patients receiving intravenous sedation.
Mohamed Elsayed Ahmed Allawy +5 more
doaj +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Intensive care unit sedation: nurses monitoring techniques
reservedDescrizione delle varie tecniche di monitoraggio in relazione alle problematiche conseguenti alla sedazione in terapia intensiva, con analisi delle cause principali di scompenso nel paziente.Description of the various monitoring techniques in ...
SATTIN, ALESSIA
core