Results 141 to 150 of about 178,193 (264)

Effect of Betahistine on Daytime Sedation and Metabolic Parameters in Patients with Schizophrenia on Second-generation Antipsychotics. [PDF]

Indian J Psychol Med
Mamidipalli SS, Sristi L, Malathesh BC, Tikka SK, Eerike M.   +4 more
europepmc   +1 more source

Conscious sedation [PDF]

British Dental Journal, 2008
openaire   +3 more sources

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Remimazolam <i>versus</i> propofol for procedural sedation in hysteroscopic surgery: a meta-analysis of randomized controlled trials. [PDF]

PeerJ
Liu J, Lu KK, Chen J, Chen W, Pang H, Song J, Wang Y.   +6 more
europepmc   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Non-anesthesiologist Administered Propofol Sedation in ASA III Patients: A Step too Far? [PDF]

Endosc Int Open
Wu J.
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Methodological Concerns Regarding ED95 Estimation and Outcome Interpretation in the Remimazolam Dose-Finding Study for HIFU Ablation [Letter]. [PDF]

Drug Des Devel Ther
Yu S, Meng J, Li J.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Reported Safety and Sedation Outcomes of Intranasal Dexmedetomidine as a Sole Sedative for Magnetic Resonance Imaging (MRI) in Children: A Systematic Review and Meta-Analysis. [PDF]

Children (Basel)
Ajabnoor HM, Alshihri D, Albaqami F, Alghamdi L, Alhazmi LM, Alghamdi R, Ajabnoor AM, Almadfaa RO, Baamer RM.   +8 more
europepmc   +1 more source