Results 101 to 110 of about 206,888 (308)

Palliative sedation – revised recommendations [PDF]

Palliative sedation is defined as the monitored use of medications intended to induce a state of decreased or absent awareness (unconsciousness) to relieve the burden of otherwise intractable suffering in a manner ethically acceptable to the patient ...
Marta Mazzoli, Steffen Eychmüller, Eychmüller, S., Gaertner, Jan, Josiane Pralong, Mazzoli, M., Martyna Tomczyk, Beauverd, Michel, Gaertner, J., Beauverd, M., Pralong, J., Jan Gaertner, Mazzoli, Marta, Tomczyk, M., Pralong, Josiane, Michel Beauverd, Eychmüller, Steffen, Tomczyk, Martyna   +17 more
core   +1 more source

A Checklist to Document Sedation Competency

MedEdPORTAL, 2008
Introduction Pediatric procedural sedation is an area of increasing focus. In practice, many pediatricians may be called upon to provide sedation for children in diverse settings.
Karen Judy, Kathleen Webster
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Sedation in the intensive care setting

, 2012
Christopher G Hughes, Stuart McGrane, Pratik P PandharipandeVanderbilt University School of Medicine, Nashville, TN, USAAbstract: Critically ill patients are routinely provided analgesia and sedation to prevent pain and anxiety, permit invasive ...
Pandharipande PP, McGrane S, Hughes CG
core  

Risk factors for chloral hydrate sedation failure in pediatric patients: a retrospective analysis [PDF]

Korean Journal of Anesthesiology
Background This study aimed to investigate the risk factors for chloral hydrate sedation failure and complications in a tertiary children’s hospital in South Korea.
Young-Eun Jang, Jung-Bin Park, Pyoyoon Kang, Sang-Hwan Ji, Eun-Hee Kim, Ji-Hyun Lee, Hee-Soo Kim, Jin-Tae Kim   +7 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Research of sedation for dentistry : Part 3. Method of additional injection for Midazolam intravenous sedation during operation

, 2000
P(論文)We have actively used intravenous sedation with monitored conscious sedation care for cases of dental and minor oral surgical procedures under local anesthesia.
大桶,華子, 26041, 加藤,元康, OHKE,Hanako/KUDO,Masaru/KATO,Motoyasu/KAWAI,Takurou/SATO,Yuki/KATAGIRI,Kazuhito/KOKUBU,Masahiro/SHINYA,Noboru, 新家,昇, 工藤,勝, 河合,拓郎, 片桐,和人, 26039, 國分,正廣, 佐藤,雄季   +10 more
core  

Sedation protocols to reduce duration of mechanical ventilation in the ICU: a Cochrane Systematic Review

, 2016
Aims: Assess the effects of protocol-directed sedation management on the duration of mechanical ventilation and other relevant patient outcomes in mechanically ventilated intensive care unit patients.
Bucknall, T, Burmeister, E, Aitken, L. M., Aitken, Leanne M., Burmeister, Elizabeth, Mitchell, M., Bucknall, T.K., Keogh, S. J., Aitken, LM, Aitken, Leanne M, Mitchell, Marion, Kent, Bridie, Aitken, Leanne, Mitchell, M, Burmeister, E., Kent, B., Keogh, Samantha, Keogh, S, Kent, B, Bucknall, Tracey   +19 more
core   +1 more source

Analysis of procedural sedation nursing practice in the pediatric wards of a tertiary hospital in South Korea: a retrospective descriptive study [PDF]

Child Health Nursing Research
Purpose To analyze the general, clinical, and sedation-related characteristics of pediatric inpatients who received procedural sedation from pediatric sedation nurses, and to identify the incidence of sedation-related adverse events and sedation failure.
Ji-Eun Jung, Kyung-Sook Bang
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source