Results 71 to 80 of about 206,888 (308)

To Sedate or Not to Sedate? [PDF]

open access: yesJournal of Pain and Symptom Management, 2007
Sophie, Pautex, Gilbert B, Zulian
openaire   +4 more sources

Procedural Sedation and Analgesia in Children: Perspectives from Paediatric Emergency Physicians

open access: yesProceedings of Singapore Healthcare, 2010
Procedural sedation and analgesia in children is now widely practised in many emergency departments internationally. In this article, we address the general principles, indications, guidelines, medications, adverse events and future research in ...
Lai Peng Tham MBBS, MMed (Paediatrics)   +1 more
doaj   +1 more source

Korean clinical practice guidelines for diagnostic and procedural sedation [PDF]

open access: yesKorean Journal of Anesthesiology
Safe and effective sedation depends on various factors, such as the choice of sedatives, sedation techniques used, experience of the sedation provider, degree of sedation-related education and training, equipment and healthcare worker availability, the ...
Sang-Hyun Kim   +18 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Offset of pharmacodynamic effects and safety of remifentanil in intensive care unit patients with various degrees of renal impairment

open access: yes, 2003
Introduction: This open label, multicentre study was conducted to assess the times to offset of the pharmacodynamic effects and the safety of remifentanil in patients with varying degrees of renal impairment requiring intensive care. Methods: A total of
Bach, Vagn   +7 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Avaliação do uso de cetamina para sedoanalgesia de pacientes críticos [PDF]

open access: yes, 2014
Dissertação (mestrado profissional) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Cuidados Intensivos e Paliativos, Florianópolis, 2014.Objetivo: Avaliar a eficácia e segurança da cetamina para ...
Rohr, Jaqueline Flores
core  

Monitoring of sedation during neuroaxial blockade.

open access: yes, 2013
Errores del documento original. Autores: Guerrero OrriachJose Luis. Afiliación: PostgraduateResearch, Universidad Autónoma de Madrid, Facultad de Medicina, Spain. HospitalInfanta Leonor, Madrid, Spain.
Blanco, Brezo del   +4 more
core   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy